Diffusion tensor magnetic resonance imaging in the evaluation of reconstructive craniopalisty results in children with sagittal synostosis

Sladkov D.G.; Bondarenko V.P.; Lopatin A.V.

doi:https://doi.org/10.17116/operhirurg202590315

Sladkov D.G.

Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology

ORCID: 0000-0003-2638-3727

Bondarenko V.P.

Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology

ORCID: 0000-0003-3937-8855

Lopatin A.V.

Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology

ORCID: 0000-0002-0942-6695

Diffusion tensor magnetic resonance imaging in the evaluation of reconstructive craniopalisty results in children with sagittal synostosis

Authors:

Sladkov D.G., Bondarenko V.P., Lopatin A.V.

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Journal: Russian Journal of Operative Surgery and Clinical Anatomy. 2025;9(3): 5‑11

DOI: 10.17116/operhirurg202590315

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To cite this article:

Sladkov DG, Bondarenko VP, Lopatin AV. Diffusion tensor magnetic resonance imaging in the evaluation of reconstructive craniopalisty results in children with sagittal synostosis. Russian Journal of Operative Surgery and Clinical Anatomy. 2025;9(3):5‑11. (In Russ.)
https://doi.org/10.17116/operhirurg202590315

Подписка 2026 Оперативная хирургия и клиническая анатомия (Пироговский научный журнал) (Russian Journal of Operative Surgery and Clinical Anatomy)

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BACKGROUND

The clinical signs of craniosynostosis are not limited only by abnormal head shape. In addition, such patients experience morphological changes in the brain, which without timely treatment can lead to severe cognitive impairment, disability and decreased quality of life.

OBJECTIVE

The aim of this study is to evaluate brain pathways in patients with sagittal synostosis before and after surgical treatment and complex inpatient rehabilitation. Confirm the importance of craniosynostosis timely surgical correction according to the obtained data.

MATERIAL AND METHODS

The study included 6 children diagnosed with sagittal synostosis, hospitalized in the department of pediatric oncology, head and neck surgery and neurosurgery of the Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology, and Immunology. All patients underwent MRI-tractography both before and after surgical treatment and rehabilitation.

RESULTS

This study demonstrates the possibilities of MRI-tractography in the diagnosis of morphological changes and their dynamics assessment in patients with sagittal synostosis, as well as the results of the treatment including the complex of surgery and inpatient rehabilitation. This technique has low prevalence among such patients not only in Russian, but also in international practice.

CONCLUSION

It has been shown that changes in the state of the brain pathways in children with sagittal synostosis may depend on age at the time of surgery, and it has been confirmed that surgical intervention has not only a cosmetic but also a specific morphological result.

Keywords:

sagittal sinostosis

scaphocephaly

craniosynostosis

magnetic resonance imaging

tractography

children

Authors:

Sladkov D.G.

Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology

ORCID: 0000-0003-2638-3727

Bondarenko V.P.

Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology

ORCID: 0000-0003-3937-8855

Lopatin A.V.

Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology

ORCID: 0000-0002-0942-6695

Received:

24.02.2025

Accepted:

17.04.2025

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