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Belysheva T.S.

Central state medical academy of department of presidential affairs;
Research Institute of Pediatric Oncology and Hematology named after. Academician of the Russian Academy of Medical Sciences L.A. Durnova (National Medical Research Center of Oncology named after N.N. Blokhin)

Sergeev Yu.Yu.

Central state medical academy of department of presidential affairs

Mordovtseva V.V.

Russian Biotechnological University, Medical Institute of Continuing Education

Kletskaya I.S.

Russian Children’s Clinical Hospital is a branch of the Pirogov Russian National Research Medical University

Artem’eva M.A.

Central state medical academy of department of presidential affairs

Melanonychia in children: on the way to recommendations for management tactics

Authors:

Belysheva T.S., Sergeev Yu.Yu., Mordovtseva V.V., Kletskaya I.S., Artem’eva M.A.

More about the authors

Journal: Russian Journal of Clinical Dermatology and Venereology. 2025;24(5): 636‑641

DOI: 10.17116/klinderma202524051636

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MELANONYCHIA IN CHILDREN: ON THE WAY TO RECOMMENDATIONS FOR MANAGEMENT TACTICS
MELANONYCHIA IN CHILDREN: ON THE WAY TO RECOMMENDATIONS FOR MANAGEMENT TACTICS

To cite this article:

Belysheva TS, Sergeev YuYu, Mordovtseva VV, Kletskaya IS, Artem’eva MA. Melanonychia in children: on the way to recommendations for management tactics. Russian Journal of Clinical Dermatology and Venereology. 2025;24(5):636‑641. (In Russ.)
https://doi.org/10.17116/klinderma202524051636

Подписка 2026 Клиническая дерматология и венерология (Russian Journal of Clinical Dermatology and Venereology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The experience of clinical and instrumental diagnosis of 60 cases of nail plate pigmentation in children is presented in this paper and for the first time in the domestic literature. Lack of reliable information on external manifestations and management tactics of longitudinal linear melanonychia in children, assumption of its possible role in the development of nail melanoma, as well as the difficulty of carrying out a diagnostic biopsy of the nail plate matrix in the child make the article extremely relevant. The possibility of detecting atypical clinical manifestations of melanonychia in children, such as total lesion of the entire nail plate, formation of nonhomogeneous coloring of the pigment strip and/or spontaneous violation of the nail integrity is shown, detailed clinical and dermatoscopic illustrations and optimal technique of surgical intervention are presented. None of the 9 children who underwent diagnostic biopsy of the nail plate matrix was found to have a malignant tumor in histological examination. Based on the literature review and own practical experience analysis, it was concluded that it is impossible to extrapolate the characteristics of nail melanoma in adult patients to the pediatric cohort and reinterpretation of the indications for surgical intervention was proposed.

Keywords:

melanonychia
nail melanoma
dermatoscopy
biopsy
onychodystrophy
children

Authors:

Belysheva T.S.

Central state medical academy of department of presidential affairs;
Research Institute of Pediatric Oncology and Hematology named after. Academician of the Russian Academy of Medical Sciences L.A. Durnova (National Medical Research Center of Oncology named after N.N. Blokhin)

Sergeev Yu.Yu.

Central state medical academy of department of presidential affairs

Mordovtseva V.V.

Russian Biotechnological University, Medical Institute of Continuing Education

Kletskaya I.S.

Russian Children’s Clinical Hospital is a branch of the Pirogov Russian National Research Medical University

Artem’eva M.A.

Central state medical academy of department of presidential affairs

Received:

15.07.2025

Accepted:

19.08.2025

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References:

  1. Tosti A, Piraccini BM, de Farias DC. Dealing with melanonychia. Semin Cutan Med Surg. 2009;28(1):49-54.  https://doi.org/10.1016/j.sder.2008.12.004
  2. Perrin C. Tumors of the nail unit. A review. Part I: acquired localized longitudinal melanonychia and erythronychia. Am J Dermatopathol. 2013;35(6): 621-636.  https://doi.org/10.1097/DAD.0b013e31826b74b8
  3. Tsai SY, Hamilton CE, Mologousis MA, Hawryluk EB. Melanoma-like features in pediatric longitudinal melanonychia: A systematic review and meta-analysis. Pediatr Dermatol. 2024;41(4):613-620.  https://doi.org/10.1111/pde.15597
  4. Kato T, Usuba Y, Takematsu H, Kumasaka N, Tanita Y, Hashimoto K, Tomita Y, Tagami H. A rapidly growing pigmented nail streak resulting in diffuse melanosis of the nail. A possible sign of subungual melanoma in situ. Cancer. 1989;64(10):2191-2197. https://doi.org/10.1002/1097-0142(19891115)64:10<2191::aid-cncr2820641035>3.0.co;2-d
  5. Kiryu H. Malignant melanoma in situ arising in the nail unit of a child. J Dermatol. 1998;25(1):41-44.  https://doi.org/10.1111/j.1346-8138.1998.tb02344.x
  6. Antonovich DD, Grin C, Grant-Kels JM. Childhood subungual melanoma in situ in diffuse nail melanosis beginning as expanding longitudinal melanonychia. Pediatr Dermatol. 2005;22(3):210-212.  https://doi.org/10.1111/j.1525-1470.2005.22306.x
  7. Motta A, López C, Acosta A, Peñaranda C. Subungual melanoma in situ in a Hispanic girl treated with functional resection and reconstruction with onychocutaneous toe free flap. Arch Dermatol. 2007;143(12):1600-1602. https://doi.org/10.1001/archderm.143.12.1600
  8. Iorizzo M, Tosti A, Di Chiacchio N, Hirata SH, Misciali C, Michalany N, Domiguez J, Toussaint S. Nail melanoma in children: differential diagnosis and management. Dermatol Surg. 2008;34(7):974-978.  https://doi.org/10.1111/j.1524-4725.2008.34191.x
  9. Bilemjian AP, Piñeiro-Maceira J, Barcaui CB, Pereira FB. Melanonychia: the importance of dermatoscopic examination and of nail matrix / bed observation. An Bras Dermatol. 2009;84(2):185-189.  https://doi.org/10.1590/s0365-05962009000200013
  10. Tosti A, Piraccini BM, Cagalli A, Haneke E. In situ melanoma of the nail unit in children: report of two cases in fair-skinned Caucasian children. Pediatr Dermatol. 2012;29(1):79-83.  https://doi.org/10.1111/j.1525-1470.2011.01481.x
  11. Bonamonte D, Arpaia N, Cimmino A, Vestita M. In situ melanoma of the nail unit presenting as a rapid growing longitudinal melanonychia in a 9-year-old white boy. Dermatol Surg. 2014;40(10):1154-1157. https://doi.org/10.1097/01.DSS.0000452656.75377.97
  12. Woo CH, Ham SP, Choi M, Park HJ. A Case of subungual melanoma in situ in an 18-year-old girl presented with total melanonychia. Ann Dermatol. 2017;29(5):653-654.  https://doi.org/10.5021/ad.2017.29.5.653
  13. Knackstedt T, Jellinek NJ. Limitations and challenges of nail unit dermoscopy in longitudinal melanonychia. J Am Acad Dermatol. 2017;76 (2):e71-e72.  https://doi.org/10.1016/j.jaad.2016.09.049
  14. Akay BN, Kirmizi A, Bostanci S, Okcu Heper A, Farabi B. Paediatric melanoma of the nail unit with rapid progression: a case report with dermatoscopic follow-up and intraoperative dermatoscopic images. Australas J Dermatol. 2020;61(1):46-48.  https://doi.org/10.1111/ajd.13182
  15. Yan Y, Huang Y, Wang Y, Chen X, Tu P, Li H. The first Chinese case of pediatric subungual melanoma: a case report and literature review. Dermatol Ther. 2020;33(6):e13918. https://doi.org/10.1111/dth.13918
  16. Ani O, et al. Clinical and Histopathological Investigation of Pediatric Melanonychia: A Single-Center Retrospective Case Series. Ann Plast Surg. 2024;92(4S Suppl 2):S87-S90.  https://doi.org/10.1097/SAP.0000000000003865
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