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Khryanin A.A.

Novosibirsk State Medical University;
Association of obstetrician-gynecologists and dermatologists

Nadeev A.P.

Novosibirsk State Medical University

Russkikh M.V.

Novosibirsk State Medical University

Bocharova V.K.

Pavlov First Saint Petersburg State Medical University

Combination of seborrheic dermatitis and HIV infection: a literature review with a clinical case

Authors:

Khryanin A.A., Nadeev A.P., Russkikh M.V., Bocharova V.K.

More about the authors

Journal: Russian Journal of Clinical Dermatology and Venereology. 2021;20(3‑2): 125‑133

DOI: 10.17116/klinderma202120032125

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Table of contents

COMBINATION OF SEBORRHEIC DERMATITIS AND HIV INFECTION: A LITERATURE REVIEW WITH A CLINICAL CASE
COMBINATION OF SEBORRHEIC DERMATITIS AND HIV INFECTION: A LITERATURE REVIEW WITH A CLINICAL CASE

To cite this article:

Khryanin AA, Nadeev AP, Russkikh MV, Bocharova VK. Combination of seborrheic dermatitis and HIV infection: a literature review with a clinical case. Russian Journal of Clinical Dermatology and Venereology. 2021;20(3‑2):125‑133. (In Russ.)
https://doi.org/10.17116/klinderma202120032125

Подписка 2026 Клиническая дерматология и венерология (Russian Journal of Clinical Dermatology and Venereology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Information on HIV-associated seborrheic dermatitis (SD) is presented. Issues of etiology and pathogenesis of SD are discussed. Particular attention is paid to the issues of the clinical course of SD at the HIV infection: SD is more severe, progresses rapidly, widespread and difficult to treat. For the development of SD a combination of 3 main factors is necessary: colonization of the skin by Malasezia spp., high activity of the sebaceous glands which lipids the fungi are used in the process of vital activity, and the presence of individual susceptibility of the macro-organism. In view of the highest incidence of SD in HIV infection, the new hypotheses and concepts of the combination of these diseases are discussed. In particular, significant changes are noted in the lipid fractions of HIV-positive patients including a decrease in squalene concentration and an increase in cholesterol and cholesterol ester levels, which contributes to the hyper-colonization of the skin by the yeast-like fungi Malasezia spp. and their transition into a pathogenic mycelial form. SD is included in the spectrum of pathological conditions in HIV infection and requires special attention of specialists to patients from high-risk groups that is important for the timely detection and treatment of patients with HIV infections and targeted correction of the clinical manifestations of SD. A clinical case demonstrating a severe course of SD associated with HIV infection is presented.

Keywords:

seborrheic dermatitis
HIV infection
etiology
pathogenesis
Malasezia spp
lipid profile of the skin
combination of seborrheic dermatitis and HIV infection

Authors:

Khryanin A.A.

Novosibirsk State Medical University;
Association of obstetrician-gynecologists and dermatologists

Nadeev A.P.

Novosibirsk State Medical University

Russkikh M.V.

Novosibirsk State Medical University

Bocharova V.K.

Pavlov First Saint Petersburg State Medical University

Received:

22.08.2020

Accepted:

05.04.2021

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