Pathogenesis and pathological anatomy of chlamydial infections

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The review presents modern view on the global problem of chlamydial infections. Current nomenclature of chlamydiae was adduced. Epidemiology, etiology, clinical features, pathogenesis, diagnosis and treatment of chlamydiosis received full coverage. The potential involvement of chlamydiae in the progression of various infectious and somatic diseases was revealed. Special attention was paid to pathomorphological alterations in human tissues, which develop during primary infection with chlamydia as well as during chronic infection. Key problems were demonstrated: underestimation of prevalence of chlamydiae among humans in worldwide clinical practice, the difficulty of detection of extragenital chlamydiosis, the lack of effective methods for diagnosis and treatment of persistent forms, the paucity of descriptions of pathomorphological picture of human chlamydiosis, the absence of specific prevention of infection.

Keywords:

chlamydia

infection

chlamydiosis

pathogenesis

Authors:

Drozdovskaya P.A.

Almazov National Medical Research Centre;
North-Western State Medical University named after I.I. Mechnikov

ORCID: 0009-0005-9617-9344

Zinserling V.A.

Almazov National Medical Research Centre;
North-Western State Medical University named after I.I. Mechnikov;
S.P. Botkin Clinical Infectious Diseases Hospital

ORCID: 0000-0001-7361-1927

Received:

23.04.2024

Accepted:

26.06.2024

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