Seborrheic dermatitis: current ideas of the etiology, pathogenesis, and treatment approaches

Polonskaya A.S.; Shatokhina E.A.; Kruglova L.S.

doi:https://doi.org/10.17116/klinderma202019041451

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Abstract:

Seborrheic dermatitis (SD) is a chronic recurrent inflammatory skin disease, which is characterized by changes in the quantitative and qualitative composition of sebum, with a predominant localization of rashes in areas rich in sebaceous glands (scalp, face, behind-the-ear area, upper body, large folds). In foreign literature, synonyms can be found such as seborrheic eczema, dandruff, pityriasis capitis. The prevalence of SD is 2-11% in the population, in immunocompromised patients — 75-93%. There are 3 peaks in the incidence of SD: the neonatal period (70% among children in the first 3 months of life), the puberty period, and at 40-70 years. The clinical picture may vary depending on the location and severity of the disease. The relevance of the study of SD is due to its widespread prevalence, the localization of rashes in visible areas of the skin and the persistence of the course, which significantly impairs the quality of life of patients. The literature review provides general information about SD, scales for course severity score, summarizes modern views on the etiology and pathogenesis, and also reflects the results of studies evaluating the effectiveness of various groups of drugs and non-drug methods in the treatment of this dermatosis.

Keywords:

seborrheic dermatitis

course severity score

etiology

pathogenesis

treatment

Authors:

Polonskaya A.S.

Central State Medical Academy of Administrative Directorate of the President of the Russian Federation

Shatokhina E.A.

Central State Medical Academy of Administrative Directorate of the President of the Russian Federation

Kruglova L.S.

Central State Medical Academy of Department of Presidential Affairs

Scopus AuthorID: 24168854300
ORCID: 0000-0002-5044-5265

Received:

05.02.2020

Accepted:

27.05.2020

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References:

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