Despite the development of new surgical and biomedical technologies, pressure sores are still a common problem worldwide, affecting both inpatient and outpatient patients. Modern medicine offers two approaches to treating pressure sores: conservative and surgical. Both methods have significant risks of complications, and the lack of clear indications for their use poses a challenge for healthcare professionals.

OBJECTIVE

To evaluate the benefits of treating decubital ulcers using cold plasma as part of a combined treatment.

MATERIAL AND METHODS

133 patients — 220 decubital ulcers of various stages of lesion. All patients, along with the accepted methods of treatment, underwent electro, radiofrequency treatment of decubital ulcers according to indications, as well as treatment with exogenous nitrogen monoxide in a therapeutic mode before closing wound defects with wound coatings at each manipulation.

RESULTS

The results showed positive dynamics in all patients in the form of the cessation of inflammatory reactions, the transition of severe stages to lighter ones with active reparation in the form of filling cavities with active granulation tissue or epithelization. There were no cases of lethality.

CONCLUSION

The inclusion of electro and radiofrequency equipment with NO effect in the local therapy of decubital ulcers, as well as the use of a nitric oxide generator in combination with known methods of treating bedsores, provides a more significant therapeutic effect, allowing for the rapid reduction of inflammatory processes and the achievement of anatomical and physiological healing of bedsores while maintaining functional capacity. This has been demonstrated through the successful treatment of 133 patients with 220 bedsores in 2024—2025, who are being treated for their underlying condition in various departments, including intensive care units, particularly in patients who are on mechanical ventilation and ECMO.