Differential diagnosis of coccidioidomycosis manifested by peripheral pulmonary lesion

Chashchina M.V.

Central TB Research Institute (CTRI)

ORCID: 0000-0002-0257-5145

Sadovnikova S.S.

Central TB Research Institute (CTRI);
Russian Medical Academy of Continuous Professional Education

ORCID: 0000-0002-6589-2834

Chesalina Ya.O.

Central TB Research Institute (CTRI)

ORCID: 0000-0003-1049-5994

Briginevich V.E.

Central TB Research Institute (CTRI)

ORCID: 0009-0008-2799-1293

Bagirov M.A.

Central TB Research Institute (CTRI);
Russian Medical Academy of Continuous Professional Education

ORCID: 0000-0001-9788-1024

Differential diagnosis of coccidioidomycosis manifested by peripheral pulmonary lesion

Authors:

Chashchina M.V., Sadovnikova S.S., Chesalina Ya.O., Briginevich V.E., Bagirov M.A.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2024;(8): 77‑85

DOI: 10.17116/hirurgia202408177

Downloaded: 8

Contact the author

Table of contents

To cite this article:

Chashchina MV, Sadovnikova SS, Chesalina YaO, Briginevich VE, Bagirov MA. Differential diagnosis of coccidioidomycosis manifested by peripheral pulmonary lesion. Pirogov Russian Journal of Surgery. 2024;(8):77‑85. (In Russ.)
https://doi.org/10.17116/hirurgia202408177

Подписка 2025 (Pirogov Russian Journal of Surgery)

Close metadata

Recommended articles:

Anatomical predictors of classical trigeminal neuralgia. Russian Journal of Pain. 2023;(4):5-10

Clinical features and modern diagnostic criteria of the disease associated with myelin oligodendrocyte glycoprotein antibody disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;(11):47-56

Diagnostic potential of magnetic resonance spectroscopy in cognitive impairment in the elderly. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;(11):105-110

Laboratory diagnostics of «key» sexually transmitted infections (literature review). Part 1. Russian Journal of Clinical Dermatology and Venereology. 2023;(6):643-650

Laboratory diagnostics of neurosyphilis: ways of optimization. Part 1. «Classical» research methods. Russian Journal of Clinical Dermatology and Venereology. 2023;(6):652-660

Use of Atezolizumab in patients with advanced small cell lung cancer. P.A. Herzen Journal of Oncology. 2023;(6):63-67

Plasma and salivary acetylcholinesterase activity in amyotrophic lateral sclerosis. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(1):128-134

Diagnostics of HIV-infection in the Chechen Republic: current state and prospects. Russian Journal of Preventive Medicine. 2024;(1):17-24

Endobronchial hamartoma. P.A. Herzen Journal of Oncology. 2024;(1):59-62

Laboratory diagnosis of «key» sexually transmitted infections. Part II. Russian Journal of Clinical Dermatology and Venereology. 2024;(1):6-11

We present this clinical case as a demonstration of difficulties in differential diagnosis of pulmonary coccidioidomycosis. Differential diagnostics of peripheral pulmonary lesion performed using bronchoscopy with BAL and TBCB and video-assisted thoracic surgery (VATS) biopsy. Diagnostic specimens were tested using microbiological (luminescent microscopy, culture for M. tuberculosis (BACTEC MGIT960 and Lowenstein-Jensen Medium), RT-PCR, cytological and morphological (hematoxylin-eosin, Ziehl—Neelsen, PAS, Grocott methenamine silver (GMS) stainings) examinations. A diagnosis was verified correctly In Russia the country is not endemic for coccidioidomycosis and patient was treated accordingly. Diagnostics of peripheral pulmonary lesions requires of multidisciplinary approaches. Morphological examination, based on detection of only granulomatous inflammation in lung biopsy cannot be used for finally DS and requires microbiological confirmation for TB or other infections, and dynamic monitoring of the patient with concordance their anamnesis vitae and morbi.

Keywords:

coccidioidomycosis

fungal infections

diagnostics

peripheral pulmonary lesion

bronchoscopy

transbronchial cryobiopsy of lung (TBCB)

VATS surgical biopsy

Authors:

Chashchina M.V.

Central TB Research Institute (CTRI)

ORCID: 0000-0002-0257-5145

Sadovnikova S.S.

Central TB Research Institute (CTRI);
Russian Medical Academy of Continuous Professional Education

ORCID: 0000-0002-6589-2834

Chesalina Ya.O.

Central TB Research Institute (CTRI)

ORCID: 0000-0003-1049-5994

Briginevich V.E.

Central TB Research Institute (CTRI)

ORCID: 0009-0008-2799-1293

Bagirov M.A.

Central TB Research Institute (CTRI);
Russian Medical Academy of Continuous Professional Education

ORCID: 0000-0001-9788-1024

Received:

28.12.2023

Accepted:

11.01.2024

List of references:

Herrick KR, Trondle ME, Febles TT. Coccidioidomycosis (Valley Fever) in Primary Care. American Family Physician. 2020;101(4):221-228.
Popova AYu, Toporkov AV, Lipnitsky AV, Popovets NV, Viktorov DV. Distribution of especially dangerous mycoses in the world. Journal of Microbiology, Epidemiology and Immunobiology. 2016;3:120-126. (In Russ.).
Taylor JW, Barker BM. The endozoan, small-mammal reservoir hypothesis and the life cycle of Coccidioides species. Medical Mycology. 2019;57(S1):16-20. https://doi.org/10.1093/mmy/myy039
Pappagianis D. Epidemiology of Coccidioidomycosis. In: Stevens DA, ed. Coccidioidomycosis. Current Topics in Infectious Disease. MA: Springer; 1980;63-85. https://doi.org/10.1007/978-1-4757-1712-9_4
Johnson RH, Sharma R, Kuran R, Fong I, Heidari A. Coccidioidomycosis: a review. Journal of Investigative Medicine. 2021;69(2):316-323. https://doi.org/10.1136/jim-2020-001655
Panackal AA, Hajjeh RA, Cetron MS, Warnock DW. Fungal infections among returning travelers. Clinical Infectious Diseases. 2002;35(9):1088-1095. https://doi.org/10.1086/344061
Tamerius JD, Comrie AC. Coccidioidomycosis incidence in Arizona predicted by seasonal precipitation. PloS One. 2011;6(6):e21009. https://doi.org/10.1371/journal.pone.0021009
Nel JS, Bartelt LA, van Duin D, Lachiewicz AM. Endemic Mycoses in Solid Organ Transplant Recipients. Infectious Disease Clinics of North America. 2018;32(3):667-685. https://doi.org/10.1016/j.idc.2018.04.007
Stagliano D, Epstein J, Hickey P. Fomite-transmitted coccidioidomycosis in an immunocompromised child. The Pediatric Infectious Disease Journal. 2007;26(5):454-456. https://doi.org/10.1097/01.inf.0000259231.95285.bc
Malo J, Luraschi-Monjagatta C, Wolk DM, et al. Update on the diagnosis of pulmonary coccidioidomycosis. Annals of the American Thoracic Society. 2014;11(2):243-253. https://doi.org/10.1513/AnnalsATS.201308-286FR
Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID). Accessed 29.12.20. https://www.cdc.gov/fungal/diseases/coccidioidomycosis/index.html
Ekeng BE, Davies AA, Osaigbovo II, Warris A, Oladele RO, Denning DW. Pulmonary and Extrapulmonary Manifestations of Fungal Infections Misdiagnosed as Tuberculosis: The Need for Prompt Diagnosis and Management. Journal of Fungi. 2022;8(5):460. https://doi.org/10.3390/jof8050460
Grishina MA, Kochubeeva EN, V’yuchnova NV, Antonov VA, Tkachenko GA, Alekseev VV, Lipnitsky AV. Laboratory Diagnostics of Coccidioidomycosis. Problems of Particularly Dangerous Infections. 2012;(1(111)):70-76. (In Russ.) https://doi.org/10.21055/0370-1069-2012-1(111)-70-76
Turner JF, Khoury JD, Ruckdeschel JC. Granulomatous solitary pulmonary nodule. Journal of Bronchology and Interventional Pulmonology. 2011;18(1):111-112. https://doi.org/10.1097/LBR.0b013e318206fbec
Calvani J, Feuillet S, Dorfmuller P, de Montpréville VT, Mussot S, Ghigna MR. Un cas d’infection pulmonaire importé des États-Unis. Annales de pathologie. 2017;37(2):202-205. https://doi.org/10.1016/j.annpat.2017.01.007
Kishi K, Fujii T, Takaya H, Miyamoto A, Kurosaki A, Kohno T, Yoshimura K. Pulmonary coccidioidomycosis found in healthy Japanese individuals. Respirology. 2008;13(2):252-256. https://doi.org/10.1111/j.1440-1843.2008.01232.x
Popova VV. Kokcidioidomikoz legkih: opisanie klinicheskogo sluchaja. Mechnikovskie chtenija — 2018. 91-ja Vserossijskaja nauchno-prakticheskaja konferencija s mezhdunarodnym uchastiem: programma. SPb.: Izd-vo SZGMU im. I.I. Mechnikova; 2018. (In Russ.).
Aravijskij RA, Klimko NN, Vasil’eva NV. Diagnostika mikozov. StPb.: SPbMAPO; 2004. (In Russ.).
Bolezni organov dyhanija. Pnevmomikozy. Pod. red. NR Paleeva. M.: Medicina; 2000. (In Russ.).
Lipnickij AV, Polovec NV, Murugova AA. Coinfections of Covid-19 and endemic mycoses. Advances in medical mycology. 2022;23:71-77. (In Russ.).
Yang X, Song Y, Liang T, Wang Q, Li R, Liu W. Application of laser capture microdissection and PCR sequencing in the diagnosis of Coccidioides spp. infection: A case report and literature review in China. Emerging Microbes & Infections. 2021;10(1):331-341. https://doi.org/10.1080/22221751.2021.1889931

Close metadata