The long-term consequences of distal venous thrombosis as well as diseases of femoral and popliteal veins remain poorly known. The prognostic significance of these variants of deep venous thrombosis (DVT) is ambiguous unlike that of iliocaval thrombosis that usually leads to the development of severe forms of post-thrombotic disease of the lower extremities. Investigations into the risk factors of DVT demonstrated that in the case of distal localization of the disorder they are different from those in the case of proximal thrombosis and pulmonary embolism. The distal localization of DVT is characterized by the lower frequency of relapses and pulmonary embolism. Despite a large number of published studies on long-term consequences of distal venous thrombosis, opinions differ as regards practically all aspects of the problem being considered, from the optimal treatment modalities, its duration, and effectiveness to the influence of different factors on the probability of the development of post-thrombotic disease depending on  the specific features of venous diseases and  the mode of their treatment. These considerations are especially relevant in connection with distal DVT and thrombosis that does not spread above the femoral veins. Although the number of the patients with this variant of DVT is much greater than that of the patients with iliocaval thrombosis, their fate in the late period of the disease remains virtually unknown. In this context, it is important to evaluate the long-term results of the treatment of  thromboses localized below the inguinal fold level.