Features of perioperative period in patients with cardiovascular-kidney-metabolic syndrome

Lutfarakhmanov I.I.; Grazhdankin A.A.; Mironov P.I.

doi:https://doi.org/10.17116/anaesthesiology202502126

Lutfarakhmanov I.I.

Bashkir State Medical University

ORCID: 0000-0002-5829-5054

Grazhdankin A.A.

Bashkir State Medical University

ORCID: 0000-0002-5874-8543

Mironov P.I.

Bashkir State Medical University

ORCID: 0000-0002-9016-9461

Features of perioperative period in patients with cardiovascular-kidney-metabolic syndrome

Authors:

Lutfarakhmanov I.I., Grazhdankin A.A., Mironov P.I.

More about the authors

Journal: Russian Journal of Anesthesiology and Reanimatology. 2025;(2): 26‑33

DOI: 10.17116/anaesthesiology202502126

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To cite this article:

Lutfarakhmanov II, Grazhdankin AA, Mironov PI. Features of perioperative period in patients with cardiovascular-kidney-metabolic syndrome. Russian Journal of Anesthesiology and Reanimatology. 2025;(2):26‑33. (In Russ.)
https://doi.org/10.17116/anaesthesiology202502126

Использование инфографики авторами научных работ

BACKGROUND

The recent concept of cardiovascular-kidney-metabolic syndrome (CVKMS) is defined as a health disorders associated with obesity, diabetes mellitus, chronic kidney disease and cardiovascular diseases. This concept is aimed at improving the multidisciplinary approach to prevention, risk stratification and treatment of these disorders.

OBJECTIVE

To substantiate the feasibility for selection of CVKMS within metabolic syndrome in anesthetic support of non-cardiac surgeries in high-risk patients.

MATERIAL AND METHODS

One hundred and two patients were divided into the CVKMS group (n=34) and the metabolic syndrome group (n=68). Severity of postoperative complications was classified according to the Clavien—Dindo definitions. Length of postoperative hospital-stay was analyzed.

RESULTS

Patients with CVKMS had a significantly higher rate of metabolic syndrome components: arterial hypertension, obesity and diabetes mellitus (p<0.005 for all comparisons). The number of patients with complications was significantly higher in the CVKMS group (p=0.005). Postoperative complications Clavien–Dindo grade II and III were significantly more common in the CVKMS group (p=0.001 and p< 0.001; respectively). Length of postoperative hospital-stay was significantly longer in the CVKMS group (p=0.022).

CONCLUSION

Compared to metabolic syndrome, patients with CVKMS have a higher incidence of perioperative adverse events and longer hospital-stay after non-cardiac surgery. Thus, CVKMS should be considered when providing anesthetic support in high-risk patients.

Keywords:

cardiovascular-kidney-metabolic syndrome

non-cardiac surgery

general anesthesia

complications

outcomes

Authors:

Lutfarakhmanov I.I.

Bashkir State Medical University

ORCID: 0000-0002-5829-5054

Grazhdankin A.A.

Bashkir State Medical University

ORCID: 0000-0002-5874-8543

Mironov P.I.

Bashkir State Medical University

ORCID: 0000-0002-9016-9461

Received:

06.09.2024

Accepted:

31.10.2024

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References:

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