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Mai R.B.

Vladimirsky Moscow Regional Research Clinical Institute;
Pirogov Russian National Research Medical University

Reshchikov D.A.

Russian Children’s Clinical Hospital — Pirogov Russian National Research Medical University

Vasilyev I.G.

Pirogov Russian National Research Medical University

Popov V.E.

Vladimirsky Moscow Regional Research Clinical Institute

Tarasova E.M.

Russian Children’s Clinical Hospital — Pirogov Russian National Research Medical University

Senchenko M.A.

Blokhin National Medical Research Center of Oncology

Melanotic neuroectodermal tumor of infancy. Clinical case of large fontanel tumor and literature review

Authors:

Mai R.B., Reshchikov D.A., Vasilyev I.G., Popov V.E., Tarasova E.M., Senchenko M.A.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2022;86(6): 58‑65

DOI: 10.17116/neiro20228606158

Read: 3321 times

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Table of contents

MELANOTIC NEUROECTODERMAL TUMOR OF INFANCY. CLINICAL CASE OF LARGE FONTANEL TUMOR AND LITERATURE REVIEW
MELANOTIC NEUROECTODERMAL TUMOR OF INFANCY. CLINICAL CASE OF LARGE FONTANEL TUMOR AND LITERATURE REVIEW

To cite this article:

Mai RB, Reshchikov DA, Vasilyev IG, Popov VE, Tarasova EM, Senchenko MA. Melanotic neuroectodermal tumor of infancy. Clinical case of large fontanel tumor and literature review. Burdenko's Journal of Neurosurgery. 2022;86(6):58‑65. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20228606158

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Melanotic neuroectodermal tumor of infancy (MNTI) is a neonatal tumor with progressive growth and high recurrence rate. Aggressive growth and localization of tumor often lead to significant cosmetic defects of cranial and facial bones. The authors report MNTI in a 6-month-old boy with lesion of the large fontanel. Total resection was followed by recurrence after 3 weeks. Repeated resection with subsequent radiotherapy was performed. The follow-up period was 6 months after repeated resection. There was no tumor growth throughout this period. Considering this case and world experience, we can conclude that treatment strategy for MNTI is still unclear.

Keywords:

melanotic neuroectodermal tumor of infancy
newborns
radiotherapy
pediatric neurosurgery

Authors:

Mai R.B.

Vladimirsky Moscow Regional Research Clinical Institute;
Pirogov Russian National Research Medical University

Reshchikov D.A.

Russian Children’s Clinical Hospital — Pirogov Russian National Research Medical University

Vasilyev I.G.

Pirogov Russian National Research Medical University

Popov V.E.

Vladimirsky Moscow Regional Research Clinical Institute

Tarasova E.M.

Russian Children’s Clinical Hospital — Pirogov Russian National Research Medical University

Senchenko M.A.

Blokhin National Medical Research Center of Oncology

Received:

21.04.2022

Accepted:

19.08.2022

Close metadata

References:

  1. Jeon HJ, Kong DS, Shin HJ. Melanotic neuroectodermal tumor of infancy: A case report. Child’s Nervous System. 2008;24(12):1489-1492. https://doi.org/10.1007/s00381-008-0671-z
  2. Nicosia G, Spennato P, Aliberti F, Cascone D, Quaglietta L, Errico ME, Muto M, Ionna F, Cinalli G. Giant melanotic neuroectodermal tumor of infancy (melanotic progonoma) of the head and neck: Report of a malignant case. Journal of Neurosurgery: Pediatrics. 2017;19(5):538-545.  https://doi.org/10.3171/2016.11.PEDS16509
  3. Ebel F, Thieringer FM, Kunz C, Klein-Franke A, Scheinemann K, Guzman R, Soleman J. Melanotic neuroectodermal tumor of infancy to the skull: case-based review. Child’s Nervous System. 2020;36(4):679-688.  https://doi.org/10.1007/s00381-020-04509-6
  4. Naidoo J, Potgieter L, Wieselthaler N, Pillay K. Melanotic neuroectodermal tumour of infancy, a rare cause for a bump on the head. Child’s Nervous System. 2013;29(1):167-172.  https://doi.org/10.1007/s00381-012-1940-4
  5. Kruse-Lösler B, Gaertner C, Bürger H, Seper L, Joos U, Kleinheinz J. Melanotic neuroectodermal tumor of infancy: systematic review of the literature and presentation of a case. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2006;102(2):204-216.  https://doi.org/10.1016/j.tripleo.2005.08.010
  6. Moreau A, Galmiche L, Minard-Colin V, Rachwalski M, Belhous K, Orbach D, Joly A, Picard A, Kadlub N. Melanotic neuroectodermal tumor of infancy (MNTI) of the head and neck: A French multicenter study. Journal of Cranio-Maxillo-Facial Surgery. 2018;46(2):201-206.  https://doi.org/10.1016/j.jcms.2017.12.001
  7. Mengide JP, Mantese B. Melanotic neuroectodermal tumor of infancy arising from the skull: report of an unusual case, review of the literature, and a diagnostic approach. Child’s Nervous System. 2020;36(3):469-475.  https://doi.org/10.1007/s00381-019-04476-7
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