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Rusakova M.I.

Pavlov First Saint Petersburg Medical University

Manzhurova M.I.

Saint Petersburg State University

Zakaryan A.N.

Pavlov First Saint Petersburg Medical University

Lopatina S.L.

Kirov Military Medical Academy

Frolova E.F.

Kirov Military Medical Academy

Raevskiy K.P.

Kirov Military Medical Academy

The gut microbiota in bipolar disorder

Authors:

Rusakova M.I., Manzhurova M.I., Zakaryan A.N., Lopatina S.L., Frolova E.F., Raevskiy K.P.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(11): 28‑33

DOI: 10.17116/jnevro202412411128

Read: 2896 times

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Table of contents

THE GUT MICROBIOTA IN BIPOLAR DISORDER
THE GUT MICROBIOTA IN BIPOLAR DISORDER

To cite this article:

Rusakova MI, Manzhurova MI, Zakaryan AN, Lopatina SL, Frolova EF, Raevskiy KP. The gut microbiota in bipolar disorder. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(11):28‑33. (In Russ.)
https://doi.org/10.17116/jnevro202412411128

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The gut microbiota is a community of microorganisms that live in the digestive tract of living beings and form bidirectional symbiotic relationships with them. It is known that gut bacteria play an important role in maintaining the functioning of the host organism, and disruption in the normal composition of the gut microbiota can contribute to the development of many diseases. The study of microbiota has been gaining popularity in recent years, and its influence on the course of various pathological conditions is becoming more and more undeniable. Due to the growing evidence supporting the connection between the gastrointestinal tract, microbiota and brain, the term «microbiota—gut—brain axis» has appeared. It regulates the functions of the central nervous system, affecting the mood, behavior of the host and, therefore, is involved in the pathogenesis of various mental disorders. Bipolar disorder, a long–known affective mental illness of an endogenous origin, is no exception. The review analyzes the evidence on the relationship between gut microbiota and bipolar disorder, as well as an overview of additional treatments for this disease that affect the microflora of the human body.

Keywords:

gut microbiota
bipolar disorder
depression
mania
probiotics

Authors:

Rusakova M.I.

Pavlov First Saint Petersburg Medical University

Manzhurova M.I.

Saint Petersburg State University

Zakaryan A.N.

Pavlov First Saint Petersburg Medical University

Lopatina S.L.

Kirov Military Medical Academy

Frolova E.F.

Kirov Military Medical Academy

Raevskiy K.P.

Kirov Military Medical Academy

Received:

26.12.2023

Accepted:

17.07.2024

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References:

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