Traumatic brain injury: cognitive, affective disorders, and post-traumatic attacks

Timokhova A.V.; Kostyunina O.V.; Komoltsev I.G.; Less Y.E.; Guekht A.B.; Gulyaeva N.V.

doi:https://doi.org/10.17116/jnevro202512512129

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Abstract:

Traumatic brain injury (TBI) is an urgent problem of modern healthcare due to its high prevalence and multiple consequences. This review addresses the main features of TBI, mechanisms of brain injury, current clinical studies, as well as cognitive and affective disorders and the development of post-traumatic attacks.

Keywords:

traumatic brain injury

cognitive disorders

affective disorders

post-traumatic attacks

Authors:

Timokhova A.V.

Moscow Research and Clinical Center for Neuropsychiatry

ORCID: 0000-0002-5707-3863

Kostyunina O.V.

Institute of Higher Nervous Activity and Neurophysiology

ORCID: 0009-0009-5281-8561

Komoltsev I.G.

Moscow Research and Clinical Center for Neuropsychiatry;
Institute of Higher Nervous Activity and Neurophysiology

ORCID: 0000-0002-4918-6411

Less Y.E.

Moscow Research and Clinical Center for Neuropsychiatry

ORCID: 0009-0004-2034-0894

Guekht A.B.

Moscow Research and Clinical Center for Neuropsychiatry;
Pirogov Russian National Research Medical University

ORCID: 0009-0002-5667-9617

Gulyaeva N.V.

Moscow Research and Clinical Center for Neuropsychiatry;
Institute of Higher Nervous Activity and Neurophysiology

ORCID: 0000-0002-5380-7954

Received:

27.09.2025

Accepted:

29.09.2025

Conflict of Interest :

The study was conducted as part of the research project «Neurological and Psychiatric Complications of Traumatic Brain Injury: Biomarkers and Approaches to Their Correction,» conducted at the Z.P. Solovyov Research and Practical Psychoneurological Center of the Moscow Department of Health.

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