The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.
Matveeva M.V.
Siberian State Medical University
Samoilova Iu.G.
Siberian State Medical University
Sarcopenia as a non-motor symptom of Parkinson’s disease
Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(9): 15‑22
Views: 954
Downloaded: 2
To cite this article:
Zhukova NG, Matveeva MV, Kazantseva PE, Samoilova IuG, Masenko AYa, Gaponova OV, Zhukova IA. Sarcopenia as a non-motor symptom of Parkinson’s disease. S.S. Korsakov Journal of Neurology and Psychiatry.
2024;124(9):15‑22. (In Russ.)
https://doi.org/10.17116/jnevro202412409115
Sarcopenia is a progressive generalized skeletal muscle disease that is accompanied by an accelerated loss of muscle mass and function, affecting the quality of life and the ability to perform self-care. The prevalence of sarcopenia in the world today ranges from 10 to 25%, which represents a certain danger as it is a prognostic factor for possible injury and increased disability in the elderly population. Sarcopenia often accompanies a large number of different diseases, including neurodegenerative ones, so it is actively studied in this category of patients, for example, as one of the early symptoms of Parkinson’s disease (PD). PD and sarcopenia have overlapping pathophysiological mechanisms of muscle fiber loss: inflammation, muscle autophagy, oxidative stress and apoptosis. Loss of muscle mass due to malnutrition is common in PD. According to some studies, the prevalence of sarcopenia in PD varies from 6 to 55.8%; weakness and sarcopenia are more common in patients with PD than in society as a whole, which is associated with an unfavorable course of the disease. The presence of both diseases simultaneously in one patient can impose certain restrictions on the treatment of the patient, worsen his physical and mental condition, which determines the need for early detection of sarcopenia in patients with PD.
Keywords:
Authors:
Matveeva M.V.
Siberian State Medical University
Samoilova Iu.G.
Siberian State Medical University
Received:
28.04.2024
Accepted:
06.06.2024
List of references:
Close metadata
Email Confirmation
An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.
Email Confirmation
Log in to the site using your account in one of the services
We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.