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Kulikova M.S.

National Medical Research Center for Therapy and Preventive Medicine

Eganyan R.A.

National Medical Research Center for Therapy and Preventive Medicine

Impact of alcohol consumption on nature of nutrition, metabolism and human target organs. Part 1. Metabolic dysfunction

Authors:

Kulikova M.S., Eganyan R.A.

More about the authors

Journal: Russian Journal of Preventive Medicine. 2024;27(8): 87‑93

DOI: 10.17116/profmed20242708187

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IMPACT OF ALCOHOL CONSUMPTION ON NATURE OF NUTRITION, METABOLISM AND HUMAN TARGET ORGANS. PART 1. METABOLIC DYSFUNCTION
IMPACT OF ALCOHOL CONSUMPTION ON NATURE OF NUTRITION, METABOLISM AND HUMAN TARGET ORGANS. PART 1. METABOLIC DYSFUNCTION

To cite this article:

Kulikova MS, Eganyan RA. Impact of alcohol consumption on nature of nutrition, metabolism and human target organs. Part 1. Metabolic dysfunction. Russian Journal of Preventive Medicine. 2024;27(8):87‑93. (In Russ.)
https://doi.org/10.17116/profmed20242708187

 
Подписка 2025-2 (Russian Journal of Preventive Medicine)
 
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This review summarizes data on alcohol consumption as a risk factor for morbidity and mortality. The issues of metabolic dysfunction in alcohol consumption are considered. Special attention is paid to the analysis of data on target organs’ damage, namely liver, intestine, brain, as well as on the development of sarcopenic obesity and metabolic syndrome. Search and generalization of sources from PubMed, eLibrary, Scopus databases, published from 2011 to 2023, were performed in order to achieve the review objective. Data search was done on November 1, 2023 using the following keywords: alcohol, alcohol consumption, alcoholic liver disease, metabolic dysfunction, intestinal microbiota, sarcopenia. A number of publications equal 44 were selected as a result of the analysis. The review also presents 4 primary sources dated earlier than 2011, as they provided valuable information on fundamental researches on alcohol consumption and metabolic disorders. It has been concluded that the therapeutic approach to the prevention and treatment of patients with alcohol-induced liver injury until cirrhosis should be focused on the axis of fat tissue — liver — intestine modification.

Keywords:

alcohol
alcohol consumption
nutrition
alcoholic liver disease
metabolic dysfunction
intestinal microbiota
sarcopenia

Authors:

Kulikova M.S.

National Medical Research Center for Therapy and Preventive Medicine

Eganyan R.A.

National Medical Research Center for Therapy and Preventive Medicine

Received:

30.03.2024

Accepted:

03.04.2024

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