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Burd S.G.

Federal Center of Brain Research and Neurotechnologies;
Pirogov Russian National Research Medical University (Pirogov University)

Lebedeva A.V.

Federal Center of Brain Research and Neurotechnologies;
Pirogov Russian National Research Medical University (Pirogov University);
Research Institute of Health Care Organization and Medical Management

Rubleva Yu.V.

Federal Center of Brain Research and Neurotechnologies

Efimenko A.P.

Federal Center of Brain Research and Neurotechnologies

Pantina N.V.

Federal Center of Brain Research and Neurotechnologies

Yurchenko A.V.

Federal Center of Brain Research and Neurotechnologies

Bogomazova M.A.

Federal Center of Brain Research and Neurotechnologies

Kovaleva I.I.

Federal Center of Brain Research and Neurotechnologies

Alekseeva G.A.

Federal Center of Brain Research and Neurotechnologies

Ototoxicity caused by anti-epileptic drugs

Authors:

Burd S.G., Lebedeva A.V., Rubleva Yu.V., Efimenko A.P., Pantina N.V., Yurchenko A.V., Bogomazova M.A., Kovaleva I.I., Alekseeva G.A.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(12): 14‑19

DOI: 10.17116/jnevro202412412114

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Table of contents

OTOTOXICITY CAUSED BY ANTI-EPILEPTIC DRUGS
OTOTOXICITY CAUSED BY ANTI-EPILEPTIC DRUGS

To cite this article:

Burd SG, Lebedeva AV, Rubleva YuV, et al. . Ototoxicity caused by anti-epileptic drugs. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(12):14‑19. (In Russ.)
https://doi.org/10.17116/jnevro202412412114

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

According to the literature, a number of anti-epileptic drugs (AEDs) have an ototoxic effect. The mechanism of hearing dysfunction due to the use of AEDs is not well known. The main clinical manifestations of the cochleotoxic effect of the drugs are: tinnitus, sensorineural hearing loss, impaired pitch perception, hyperacusis. These disorders can be reversible and irreversible. Attending physicians should be careful when prescribing AEDs to patients who have had hearing impairment before, as well as diagnose hearing loss in a timely manner with subsequent correction of anti-epileptic therapy.

Keywords:

ototoxicity
sensorineural hearing loss
epilepsy
anti-epileptic drugs

Authors:

Burd S.G.

Federal Center of Brain Research and Neurotechnologies;
Pirogov Russian National Research Medical University (Pirogov University)

Lebedeva A.V.

Federal Center of Brain Research and Neurotechnologies;
Pirogov Russian National Research Medical University (Pirogov University);
Research Institute of Health Care Organization and Medical Management

Rubleva Yu.V.

Federal Center of Brain Research and Neurotechnologies

Efimenko A.P.

Federal Center of Brain Research and Neurotechnologies

Pantina N.V.

Federal Center of Brain Research and Neurotechnologies

Yurchenko A.V.

Federal Center of Brain Research and Neurotechnologies

Bogomazova M.A.

Federal Center of Brain Research and Neurotechnologies

Kovaleva I.I.

Federal Center of Brain Research and Neurotechnologies

Alekseeva G.A.

Federal Center of Brain Research and Neurotechnologies

Received:

18.07.2024

Accepted:

20.07.2024

Close metadata

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