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Tikhonova Yu.G.

Sechenov First Moscow State Medical University (Sechenov University)

Kinkulkina M.A.

Sechenov First Moscow State Medical University (Sechenov University)

Volkov A.V.

Sechenov First Moscow State Medical University (Sechenov University)

Sedelkova V.A.

Sechenov First Moscow State Medical University (Sechenov University)

Avdeeva T.I.

Sechenov First Moscow State Medical University (Sechenov University)

Izyumina T.A.

Sechenov First Moscow State Medical University (Sechenov University)

Makarova M.A.

Sechenov First Moscow State Medical University (Sechenov University)

Maximova T.N.

Sechenov First Moscow State Medical University (Sechenov University)

Brovko M.Yu.

Sechenov First Moscow State Medical University (Sechenov University)

Moiseev S.V.

First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health of the Russian Federation (Sechenov University)

Ivanets N.N.

Sechenov First Moscow State Medical University (Sechenov University)

Prevalence and risk factors of delirium in COVID-19

Authors:

Tikhonova Yu.G., Kinkulkina M.A., Volkov A.V., Sedelkova V.A., Avdeeva T.I., Izyumina T.A., Makarova M.A., Maximova T.N., Brovko M.Yu., Moiseev S.V., Ivanets N.N.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2023;123(7): 86‑92

DOI: 10.17116/jnevro202312307186

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Table of contents

PREVALENCE AND RISK FACTORS OF DELIRIUM IN COVID-19
PREVALENCE AND RISK FACTORS OF DELIRIUM IN COVID-19

To cite this article:

Tikhonova YuG, Kinkulkina MA, Volkov AV, et al. . Prevalence and risk factors of delirium in COVID-19. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;123(7):86‑92. (In Russ.)
https://doi.org/10.17116/jnevro202312307186

Подписка 2025-2 (S.S. Korsakov Journal of Neurology and Psychiatry)
 
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OBJECTIVE

To assess the frequency and risk factors of delirium in patients hospitalized with COVID-19.

MATERIAL AND METHODS

Four hundred and forty patients admitted to the Infectious Diseases Hospital of the University Clinical Hospital No.3 of Sechenov University were included in the study. The Patient Health Questionnaire (PHQ-9), the Generalized Anxiety Disorder Screening Questionnaire-7 (GAD-7), the Insomnia Severity Index (ISI), the Delirium severity rating scale (DRS-R-98) were administered.

RESULTS

Delirium was detected in 27.8% of patients. Significant risk factors were age (p=0.002), severity of respiratory failure (p=0.005), concomitant somatic disease (p=0.003), and respiratory therapy (p<0.001). There was an association between severe anxiety (p<0.001) and insomnia (p=0.07) observed at admission with the risk of developing delirium during the hospital stay.

CONCLUSION

The study reveals a high prevalence of delirium in patients with COVID-19. In order to prevent delirium and/or reduce the risk, early diagnosis and identification of preclinical forms are of particular importance.

Keywords:

COVID-19
delirium
anxiety
insomnia
mental health

Authors:

Tikhonova Yu.G.

Sechenov First Moscow State Medical University (Sechenov University)

Kinkulkina M.A.

Sechenov First Moscow State Medical University (Sechenov University)

Volkov A.V.

Sechenov First Moscow State Medical University (Sechenov University)

Sedelkova V.A.

Sechenov First Moscow State Medical University (Sechenov University)

Avdeeva T.I.

Sechenov First Moscow State Medical University (Sechenov University)

Izyumina T.A.

Sechenov First Moscow State Medical University (Sechenov University)

Makarova M.A.

Sechenov First Moscow State Medical University (Sechenov University)

Maximova T.N.

Sechenov First Moscow State Medical University (Sechenov University)

Brovko M.Yu.

Sechenov First Moscow State Medical University (Sechenov University)

Moiseev S.V.

First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health of the Russian Federation (Sechenov University)

Ivanets N.N.

Sechenov First Moscow State Medical University (Sechenov University)

Received:

13.03.2023

Accepted:

03.04.2023

List of references:

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