The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Bogolepova A.N.

Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency

Brovko E.V.

Zdorovie Goroda LLC (Zdorovie.ru)

Gavrilova S.I.

Mental Health Research Centre

Gantman M.V.

Center for Neuroeconomics and Cognitive Research of the Institute of Cognitive Neuroscience of the National Research University «Higher School of Economics»;
Foundation for Dementia Patients and their family support «AlcRus»

Dreval R.O.

Non-commercial partnership Center of Social Economics

Illarioshkin S.N.

Research Center of Neurology

Katunina E.A.

Federal Center of Brain and Neurotechnologies;
Pirogov Russian National Research Medical University

Konson C.

The International Medical Cluster Foundation;
Division of Geriatrics in Ministry of Health Southern District

Kostyuk G.P.

Alekseev Psychiatric Clinical Hospital No. 1

Kotovskaya Yu.V.

Russian Gerontological Research and Clinical Center

Levin O.S.

Russian Medical Academy of Continuous Professional Education

Litvinenko I.V.

Kirov Military Medical Academy

Medvedev V.E.

Peoples Friendship University of Russian

Mkhitaryan E.A.

Pirogov Russian National Research Medical University;
Russian Clinical and Research Center of Gerontology Pirogov — Russian National Research Medical University

Neznanov N.G.

Bekhterev National Medical Research Center for Psychiatry and Neurology;
Pavlov First Saint-Petersburg State Medical University

Onegina E.J.

Alekseev Mental-health Clinic No. 1

Parfenov V.A.

Sechenov First Moscow State Medical University

Tkacheva O.N.

Pirogov Russian National Research Medical University

Fedotova E.Yu.

Research Center of Neurology

Shchetkina A.L.

Foundation for Dementia Patients and their family support «AlcRus»

Yakhno N.N.

Sechenov First Moscow State Medical University

Roadmap for ecosystem-based approach for patients with Alzheimer disease in Russia: current needs, barriers, and possible solutions (resolution of the scientific and practical experts meeting)

Authors:

Bogolepova A.N., Brovko E.V., Gavrilova S.I., Gantman M.V., Dreval R.O., Illarioshkin S.N., Katunina E.A., Konson C., Kostyuk G.P., Kotovskaya Yu.V., Levin O.S., Litvinenko I.V., Medvedev V.E., Mkhitaryan E.A., Neznanov N.G., Onegina E.J., Parfenov V.A., Tkacheva O.N., Fedotova E.Yu., Shchetkina A.L., Yakhno N.N.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2022;122(7): 121‑131

DOI: 10.17116/jnevro2022122071121

Views: 7686

Downloaded: 119

Download PDF (RU)
Download PDF
Contact the author
Table of contents

To cite this article:

Bogolepova AN, Brovko EV, Gavrilova SI, et al. . Roadmap for ecosystem-based approach for patients with Alzheimer disease in Russia: current needs, barriers, and possible solutions (resolution of the scientific and practical experts meeting). S.S. Korsakov Journal of Neurology and Psychiatry. 2022;122(7):121‑131. (In Russ., In Engl.)
https://doi.org/10.17116/jnevro2022122071121

 
МСФ на ЯМ
Close metadata
Recommended articles:
Glymphatic dysfunction and sleep diso­rders: indi­rect effe­cts on Alzheimer’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(4):7-12
Ginkgolide B: mechanisms of neurobiological effe­cts, prospects for use in the therapy of Alzheimer’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(4):22-27
Comparative characteristics of neuropsychological and neurometabolic changes in patients with Alzheimer’s disease and vascular cognitive impairment. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(4-2):17-24
Impairment of atte­ntion and executive functions in chro­nic cere­brovascular disease and Alzheimer’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(4-2):25-32
Asse­ssment of the significance of dila­ted peri­vascular spaces and nocture arte­rial hype­rtension in the deve­lopment of Alzheimer’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(4-2):33-40
EEG changes in patients with Alzheimer’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(4-2):72-76
The role of astrocytes, circadian rhythms and light pollution in the pathogenesis of Alzheimer’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(6):20-25
Immu­nological and neuroanatomic markers of the clinical dyna­mics of MCI and pre-MCI. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(8):81-91
Expe­rience of using the combined drug Mioreol in patients with Alzheimer’s disease and mixed deme­ntia. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(9):34-43
Regu­lation of mito­phagy and mito­chondrial biogenesis by mono­carbonyl analogues of curcumin in the cere­bral cortex of rats in expe­rimental Alzheimer’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(9):109-114

The care of a patient with Alzheimer’s disease (AD) is considered from the perspective of an ecosystem, that is, a systemic approach describing effective partnership, collaboration and research aimed at creating value, involving all participants in the AD patient journey. The effectiveness of this ecosystem is only possible with the involvement of all stakeholders in its development, including patients, healthcare professionals at all levels, government agencies, private companies, and patient organizations. The unmet health care and information needs of patients with AD are a consequence of barriers in the AD ecosystem. Key barriers for the patient include low awareness and stigmatization of the disease in society, lack of quality epidemiological data, difficulties in timely diagnosis, lack of prevention programs, unpreparedness of most physicians to conduct AD patient rehabilitation, and other factors. Based on the analysis of the ecosystem of AD and the patient pathway, 10 main directions (strategies) necessary for the formation of the ecosystem were identified: conducting research in the diagnosis and epidemiology of AD, creating and implementing a cognitive health program, forming a legal framework, raising public awareness, optimizing patient routing for timely diagnosis, organizing a network of memory clinics/laboratories, creating a register of patients with dementia, developing digital solutions and supporting social projects.

Keywords:

Alzheimer’s disease
ecosystem around the patient
needs
barriers
solutions
roadmap

Authors:

Bogolepova A.N.

Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency

Brovko E.V.

Zdorovie Goroda LLC (Zdorovie.ru)

Gavrilova S.I.

Mental Health Research Centre

Gantman M.V.

Center for Neuroeconomics and Cognitive Research of the Institute of Cognitive Neuroscience of the National Research University «Higher School of Economics»;
Foundation for Dementia Patients and their family support «AlcRus»

Dreval R.O.

Non-commercial partnership Center of Social Economics

Illarioshkin S.N.

Research Center of Neurology

Katunina E.A.

Federal Center of Brain and Neurotechnologies;
Pirogov Russian National Research Medical University

Konson C.

The International Medical Cluster Foundation;
Division of Geriatrics in Ministry of Health Southern District

Kostyuk G.P.

Alekseev Psychiatric Clinical Hospital No. 1

Kotovskaya Yu.V.

Russian Gerontological Research and Clinical Center

Levin O.S.

Russian Medical Academy of Continuous Professional Education

Litvinenko I.V.

Kirov Military Medical Academy

Medvedev V.E.

Peoples Friendship University of Russian

Mkhitaryan E.A.

Pirogov Russian National Research Medical University;
Russian Clinical and Research Center of Gerontology Pirogov — Russian National Research Medical University

Neznanov N.G.

Bekhterev National Medical Research Center for Psychiatry and Neurology;
Pavlov First Saint-Petersburg State Medical University

Onegina E.J.

Alekseev Mental-health Clinic No. 1

Parfenov V.A.

Sechenov First Moscow State Medical University

Tkacheva O.N.

Pirogov Russian National Research Medical University

Fedotova E.Yu.

Research Center of Neurology

Shchetkina A.L.

Foundation for Dementia Patients and their family support «AlcRus»

Yakhno N.N.

Sechenov First Moscow State Medical University

Received:

10.06.2022

Accepted:

14.06.2022

List of references:

  1. Klinicheskie rekomendacii. Kognitivnye rasstrojstva u lic pozhilogo i starcheskogo vozrasta. Ministerstvo zdravoohranenija Rossijskoj Federacii, 2020. (In Russ.).
  2. Nichols E, Steinmetz JD, Vollset SE, et al. Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019. The Lancet Public Health. 2022;7(2):105-125.  https://doi.org/10.1016/S2468-2667(21)00249-8
  3. Jahno NN, Tkacheva ON, Gavrilova SI, et al. Kompleksnaja mezhdisciplinarnaja i mezhvedomstvennaja programma profilaktiki, rannego vyjavlenija, diagnostiki i lechenija kognitivnyh rasstrojstv u lic pozhilogo i starcheskogo vozrasta do 2025 g. 62 c. Accessed 22.03.22. (In Russ.). https://rgnkc.ru/images/pdf_documets/Antidement_plan_060919.pdf
  4. Global, regional, and national burden of Alzheimer’s disease and other dementias, 1990—2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 2019;18(1):88-106.  https://doi.org/10.1016/S1474-4422(18)30403-4
  5. Rosstat ocenil estestvennuju ubyl’ naselenija za 11 mesjacev v 945 tysjach chelovek [Electronic resource]. Interfax.ru Accessed: 22.03.2022. (In Russ.). https://www.interfax.ru/russia/813516
  6. International AD, University M. World Alzheimer Report 2021: Journey through the diagnosis of dementia. Published online September 21, 2021. Accessed 22.03.22.  https://www.alzint.org/resource/world-alzheimer-report-2021
  7. Gavrilova SI. Profilaktika bolezni Al’cgejmera — odna iz prioritetnyh zadach ne tol’ko nashego podrazdelenija, no i vsego mezhdunarodnogo nauchnogo soobshhestva. DoktorRu. 2017;1(130):7-8. (In Russ.).
  8. Nichols E, Vos T. Estimating the global mortality from Alzheimer’s disease and other dementias: A new method and results from the Global Burden of Disease study 2019. Alzheimer’s & Dementia. 2020;16(S10):e042236. https://doi.org/10.1002/alz.042236
  9. Xu J, Zhang Y, Qiu C, Cheng F. Global and regional economic costs of dementia: a systematic review. The Lancet. 2017;390:S47.  https://doi.org/10.1016/S0140-6736(17)33185-9
  10. 2022 Alzheimer’s disease facts and figures. Alzheimer’s & Dementia. 2022;18(4):700-789.  https://doi.org/10.1002/alz.12638
  11. Dementia-Storm-Horizon-Counts-Nandi-Seligman-Tortorice. IMF. Accessed 22.03.22.  https://www.imf.org/en/Publications/fandd/issues/2021/12/Dementia-Storm-Horizon-Counts-Nandi-Seligman-Tortorice
  12. Sestrinskaja pomoshh’ v geriatrii. Metodicheskie rekomendacii. SPb. 2019;110. (In Russ.).
  13. Rasporjazhenie Pravitel’stva RF №164-r ot 5 fevralja 2016 g. «Ob utverzhdenii Strategii dejstvij v interesah grazhdan starshego pokolenija v Rossijskoj Federacii do 2025 goda» [Electronic resource]. Accessed: 22.03.22. (In Russ.). https://mintrud.gov.ru/docs/government/173
  14. Rasmussen J, Langerman H. Alzheimer’s Disease — Why We Need Early Diagnosis. Degener Neurol Neuromuscul Dis. 2019;9:123-130.  https://doi.org/10.2147/DNND.S228939
  15. 2020 Alzheimer’s disease facts and figures. Alzheimers Dement. Published online 10.03.20.  https://doi.org/10.1002/alz.12068
  16. Half of primary care doctors say they aren’t ready for increase in Alzheimer’s cases. FierceHealthcare. Accessed 28.01.22.  https://www.fiercehealthcare.com/practices/half-primary-care-doctors-say-they-aren-t-ready-for-increase-alzheimer-s-cases
  17. Turner RS, Stubbs T, Davies DA, et al. Potential New Approaches for Diagnosis of Alzheimer’s Disease and Related Dementias. Frontiers in Neurology. 2020;11. Accessed 28.01.22.  https://doi.org/10.3389/fneur.2020.00496
  18. Gustavsson A, Pemberton-Ross P, Gomez Montero M, et al. Challenges in demonstrating the value of disease-modifying therapies for Alzheimer’s disease. Expert Review of Pharmacoeconomics & Outcomes Research. 2020;20(6):563-570.  https://doi.org/10.1080/14737167.2020.1822738
  19. Cummings J, Lee G, Zhong K, et al. Alzheimer’s disease drug development pipeline: 2021. A&D Transl Res & Clin Interv. 2021;7(1):34-39.  https://doi.org/10.1002/trc2.12179
  20. Trudgill S. Tansley AG. 1935: The use and abuse of vegetational concepts and terms. Ecology 16, 284—307. Progress in Physical Geography: Earth and Environment. 2007;31(5):517-522.  https://doi.org/10.1177/0309133307083297
  21. Moore JF. Predators and Prey: A New Ecology of Competition. Harvard Business Review. Published online 01.05.93. Accessed 22.03.22.  https://hbr.org/1993/05/predators-and-prey-a-new-ecology-of-competition
  22. The next wave of healthcare innovation. McKinsey. Accessed 28.01.22.  https://www.mckinsey.com/industries/healthcare-systems-and-services/our-insights/the-next-wave-of-healthcare-innovation-the-evolution-of-ecosystems
  23. Moore JF. Shared Purpose: A Thousand Business Ecosystems, a Connected Community, and the Future. Create Space Publishing Platform; 2013.
  24. Asakura T, Mallee H, Tomokawa S, et al. The ecosystem approach to health is a promising strategy in international development: lessons from Japan and Laos. Global Health. 2015;11(1):3.  https://doi.org/10.1186/s12992-015-0093-0
  25. Furst MA, Bagheri N, Salvador-Carulla L. An ecosystems approach to mental health services research. BJPsych Int. 2021;18(1):23-25.  https://doi.org/10.1192/bji.2020.24
  26. ICD-10 Version: 2019. Accessed 22.03.22.  https://icd.who.int/browse10/2019/en
  27. ICD-11 for Mortality and Morbidity Statistics. Accessed 22.03.22.  https://icd.who.int/browse11/l-m/en
  28. Reitz C, Rogaeva E, Beecham GW. Late-onset vs nonmendelian early-onset Alzheimer disease: A distinction without a difference? Neurology Genetics. 2020;6(5):e512. https://doi.org/10.1212/NXG.0000000000000512
  29. Lyketsos CG. Mental and Behavioral Disturbances in Dementia: Findings From the Cache County Study on Memory in Aging. American Journal of Psychiatry. 2000;157(5):708-714.  https://doi.org/10.1176/appi.ajp.157.5.708
  30. Jack CR, Albert MS, Knopman DS, et al. Introduction to the recommendations from the National Institute on Aging‐Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimer’s & Dementia. 2011;7(3):257-262.  https://doi.org/10.1016/j.jalz.2011.03.004
  31. Jack CR, Knopman DS, Jagust WJ, et al. Hypothetical model of dynamic biomarkers of the Alzheimer’s pathological cascade. Lancet Neurol. 2010;9(1):119-128.  https://doi.org/10.1016/S1474-4422(09)70299-6
  32. Jack CR, Knopman DS, Jagust WJ, et al. Tracking pathophysiological processes in Alzheimer’s disease: an updated hypothetical model of dynamic biomarkers. Lancet Neurol. 2013;12(2):207-216.  https://doi.org/10.1016/S1474-4422(12)70291-0
  33. Bateman RJ, Xiong C, Benzinger TLS, et al. Clinical and biomarker changes in dominantly inherited Alzheimer’s disease. N Engl J Med. 2012;367(9):795-804.  https://doi.org/10.1056/NEJMoa1202753
  34. Jack Jr. CR, Bennett DA, Blennow K, et al. NIA-AA Research Framework: Toward a biological definition of Alzheimer’s disease. Alzheimer’s & Dementia. 2018;14(4):535-562.  https://doi.org/10.1016/j.jalz.2018.02.018
  35. Tung HH, Chu KC, Lien RY, et al. The needs of caring people with dementia and their family caregivers. JCGG. 2018;9(1):3-4. 
  36. Hodgson NA, Black BS, Johnston D, et al. Comparison of Unmet Care Needs across The Dementia Trajectory: Findings from The Maximizing Independence at Home Study. J Geriatrics Palliative Care. 2014;2(2):5.  https://doi.org/10.13188/2373-1133.1000010
  37. Rosa E, Lussignoli G, Sabbatini F, et al. Needs of caregivers of the patients with dementia. Arch Gerontol Geriatr. 2010;51(1):54-58.  https://doi.org/10.1016/j.archger.2009.07.008
  38. The Impact Of Alzheimer’s On Caregivers. ASC Blog. Published October 14, 2014. Accessed 28.01.22.  https://www.asccare.com/impact-alzheimers-disease-caregivers
  39. Khanassov V, Rojas-Rozo L, Sourial R, et al. Needs of patients with dementia and their caregivers in primary care: lessons learned from the Alzheimer plan of Quebec. BMC Family Practice. 2021;22(1):186.  https://doi.org/10.1186/s12875-021-01528-3
  40. Psihosocial’naja terapija i nejrokognitivnaja reabilitacija pacientov pozhilogo vozrasta s kognitivnymi rasstrojstvami. Strukturno-funkcional’naja model’ reabilitacionnoj programmy «Klinika pamjati». Pod red. Kostjuka G.P. M.: «KDU»; 2019;332. (In Russ.).

Close metadata

Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.