Clinical and pathopsychological features of youth depression with attenuated schizophrenic symptoms

Omelchenko M.A.; Atadzhykova Yu.A.; Migalina V.V.; Nikiforova I.Yu.; Kaleda V.G.

doi:https://doi.org/10.17116/jnevro202112105112

Omelchenko M.A.

Mental Health Research Centre

SPIN RSCI: 1643-9032
Scopus AuthorID: 35773602800
ResearcherID: K-6508-2016
ORCID: 0000-0001-8343-168X

Atadzhykova Yu.A.

Mental Health Research Centre

Migalina V.V.

Mental Health Research Centre

Nikiforova I.Yu.

Mental Health Research Centre

Kaleda V.G.

Mental Health Research Centre

SPIN RSCI: 9035-3290
Scopus AuthorID: 56765570100
ResearcherID: K-5466-2013
ORCID: 0000-0002-1209-1443

Clinical and pathopsychological features of youth depression with attenuated schizophrenic symptoms

Authors:

Omelchenko M.A., Atadzhykova Yu.A., Migalina V.V., Nikiforova I.Yu., Kaleda V.G.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(5): 12‑18

DOI: 10.17116/jnevro202112105112

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To cite this article:

Omelchenko MA, Atadzhykova YuA, Migalina VV, Nikiforova IYu, Kaleda VG. Clinical and pathopsychological features of youth depression with attenuated schizophrenic symptoms. S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(5):12‑18. (In Russ.)
https://doi.org/10.17116/jnevro202112105112

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

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OBJECTIVE

To determine the clinical and pathopsychological features of youth depressions with attenuated schizophrenic symptoms (ASS), and their significance for early differential diagnostic and nosological assessment.

MATERIAL AND METHODS

Twenty young patients (19.7±3.7 years) with the first depressive episode with attenuated schizophrenic symptoms (ASS) (ICD-10 items F32.1, F32.2, F32.3) (basic group) were divided into subgroup 1 with attenuated positive symptoms — APS (19.3%) and subgroup 2 with attenuated negative symptoms — ANS (45.1%). Eleven young patients (19.4±2.9 years) with the classic depressive episode without ASS (ICD-10 items F32.1, F32.2) were included in a control group. Psychometric scales HDRS, SOPS, SANS, pathopsychological methods and Adult Personality Traits Questionnaire (APTQ) were used.

RESULTS

Statistically significant differences in the severity of depression were not found. A higher SOPS total score (p=0.006) and a greater severity of negative symptoms on SANS (p=0.006) were detected in patients of clinical groups compared with the comparison group. Distortion of the generalization process was detected in 60% of cases, impairments of immediate memorization were found in 30%, and the non-constructive nature of associations in 10%. Indirect data on greater emotional integrity of patients from the comparison group was obtained.

CONCLUSION

The presence of similar clinical and psychological abnormalities in the youth depressions with ASS allows us to attribute these phenomena to the possible risk factors for the development of schizophrenia.

Keywords:

Keyword: youth depression

attenuated schizophrenic symptoms

clinical risk

schizophrenia

Authors:

Omelchenko M.A.

Mental Health Research Centre

SPIN RSCI: 1643-9032
Scopus AuthorID: 35773602800
ResearcherID: K-6508-2016
ORCID: 0000-0001-8343-168X

Atadzhykova Yu.A.

Mental Health Research Centre

Migalina V.V.

Mental Health Research Centre

Nikiforova I.Yu.

Mental Health Research Centre

Kaleda V.G.

Mental Health Research Centre

SPIN RSCI: 9035-3290
Scopus AuthorID: 56765570100
ResearcherID: K-5466-2013
ORCID: 0000-0002-1209-1443

Received:

22.09.2020

Accepted:

16.10.2020

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References:

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