Генетика эпилепсии: успехи, проблемы и перспективы развития

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Авторами представлен детальный обзор современных достижений в области генетики эпилепсии. Отдельно рассмотрены новые взгляды на этиологию и патогенез генетических эпилептических энцефалопатий, фокальной эпилепсии и идиопатических генерализованных эпилепсий. Авторы подчеркивают значимость сделанных в генетике открытий для клинической практики, в том числе для перспектив развития персонифицированного лечения пациентов. Приведены сравнительный анализ ценности различных методов генетических исследований в диагностике эпилепсии, способы интеграции молекулярно-генетических анализов в повседневную практическую медицину.

Ключевые слова:

эпилепсия

генетика эпилепсии

молекулярно-генетические методы

идиопатическая генерализованная эпилепсия

фокальная эпилепсия

эпилептическая энцефалопатия

мультифакториальные заболевания

Авторы:

Гамирова Р.Г.

ФГАОУ ВО «Казанский (Приволжский) федеральный университет»; Казанская государственная медицинская академия — филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России

Гамирова Р.Р.

ФГАОУ ВО «Казанский (Приволжский) федеральный университет»

Есин Р.Г.

Казанская государственная медицинская академия — филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России; ФГАОУ ВО «Казанский (Приволжский) федеральный университет»

Даты поступления:

22.01.2020

Даты принятия в печать:

23.01.2020

Список литературы:

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