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Vinnikova M.A.

Sechenov First Moscow State Medical University (Sechenov University);
Moscow Research and Practical Centre on Addictions of the Moscow Department of Healthcare

Skryabin V.Yu.

Moscow Research and Practical Centre of Addictions

Clinical variants of psychoses in patients using synthetic cannabinoids (Spice)

Authors:

Vinnikova M.A., Skryabin V.Yu.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(8): 23‑26

DOI: 10.17116/jnevro202012008123

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Table of contents

CLINICAL VARIANTS OF PSYCHOSES IN PATIENTS USING SYNTHETIC CANNABINOIDS (SPICE)
CLINICAL VARIANTS OF PSYCHOSES IN PATIENTS USING SYNTHETIC CANNABINOIDS (SPICE)

To cite this article:

Vinnikova MA, Skryabin VYu. Clinical variants of psychoses in patients using synthetic cannabinoids (Spice). S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(8):23‑26. (In Russ.)
https://doi.org/10.17116/jnevro202012008123

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
МСФ на ЯМ
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Abstract:

To describe the structure of psychoses developed due to synthetic cannabinoids (Spice).

MATERIAL AND METHODS

Forty-six men, aged 18-35 years, with psychosis during abstinence were studied and followed up for 2 years.

RESULTS AND CONCLUSION

Four clinical variants with predominant delirious symptoms (27%) or hallucinatory symptoms (19%) or affective-delusions (21%) or mental automatisms (33%) were identified. The follow-up revealed the manifestations of schizophrenic process in 17% of the patients. Clinical and differential diagnostic characteristics of these variants in synthetic cannabinoids users are described.

Keywords:

synthetic cannabinoids
spice
dependence syndrome
psychosis
differential diagnosis
schizophrenia

Authors:

Vinnikova M.A.

Sechenov First Moscow State Medical University (Sechenov University);
Moscow Research and Practical Centre on Addictions of the Moscow Department of Healthcare

Skryabin V.Yu.

Moscow Research and Practical Centre of Addictions

Received:

13.07.2018

Accepted:

15.04.2019

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References:

  1. World Drug Report. 2015. Date: 10.07.18.  https://www.unodc.org/documents/wdr2015/WDR15_ExSum_R.pdf
  2. World Drug Report. 2013. Date: 10.07.18.  https://www.unodc.org/unodc/secured/wdr/wdr2013/WDR2013ExSum_R.pdf
  3. Patrikeeva ON, Ovchinnikov AA, Kormilina OM. Intoxication psychoses consumers of synthetic cannabinoids. Narcology. 2015;1(157):41-44. (In Russ.)
  4. Sofronov GA, Golovko AI, Barinov VA, Basharin VA, Bonitenko EYu, Ivanov MV. Synthetic cannabinoids. State of the problem. Narcology. 2012; 10:97-110. (In Russ.)
  5. Mechoulam R, Feigenbaum JJ, Lander N, Segal M, Järbe TU, Hiltunen AJ, Consroe P. Enantiomeric cannabinoids: stereospecificity of psychotropic activity. Experientia. 1988;9(44):762-764. 
  6. Moore TH, Zammit S, Lingford-Hughes A, Barnes TR, Jones PB, Burke M, Lewis G. Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review. Lancet. 2007;9584(370):319-328. 
  7. Müller H, Sperling W, Köhrmann M, Huttner HB, Kornhuber J, Maler JM. The synthetic cannabinoid Spice as a trigger for an acute exacerbation of cannabis induced recurrent psychotic episodes. Schizophrenia Research. 2010; 1-3(118):309-310. 
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