Cognitive rehabilitation of patients with focal brain damage

Bogolepova A.N.; Levin O.S.

doi:https://doi.org/10.17116/jnevro2020120041115

Close metadata

Recommended articles:

Improving the effectiveness of treatment of patients with post-stroke aphasia. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(10):22-28

Glial fibrillary acidic protein: is there a relationship with the course of multiple sclerosis and traumatic brain injury before the onset of multiple sclerosis?. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(10):80-84

Stroke: current state of the problem. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(11):7-18

Evaluation of the effectiveness of the drug Cortexin in combination with the use of the application Aphasia.No (Afaziyam.Net) in the correction of speech disorders in patients with cerebral infarction. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(11):147-151

Cognitive impairment in bilinguals with neurological diseases. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(12):26-29

Clinical and epidemiological indicators of stroke during the COVID-19 pandemic and in the post-COVID period in the Moscow region. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(12-2):5-11

Connectome in stroke patients. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(12-2):46-50

Neurometabolic therapy with Cerebrolysin in patients with sepsis-associated encephalopathy. Russian Journal of Anesthesiology and Reanimatology. 2024;(6):46-54

Differentiated approach to cognitive rehabilitation of patients after stroke. Problems of Balneology, Physiotherapy and Exercise Therapy. 2024;(6):5-11

Fibrin monomer in diagnosis of cardiovascular diseases. Russian Cardiology Bulletin. 2024;(4-2):113-120

Abstract:

One of the important problems of modern neurology is the cognitive impairment caused by focal brain damage in stroke and traumatic brain injury. Cognitive deficit has a negative impact on the quality of life of the patient and his environment, to a large extent hindering the possibility of a full social and professional recovery. Such patients need a comprehensive rehabilitation treatment, including cognitive rehabilitation, motor rehabilitation and drug correction. The use of cerebrolysin, the effectiveness of which in patients after stroke and head injury is confirmed by many studies, is discussed.

Keywords:

cognitive rehabilitation

stroke

traumatic brain injury

neuroplasticity

recovery

cerebrolysin

Authors:

Bogolepova A.N.

Rossiĭskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Moskva

SPIN RSCI: 6775-0279
Scopus AuthorID: 6602240836
ORCID: 0000-0002-6327-3546

Levin O.S.

Rossiĭskaia meditsinskaia akademiia poslediplomnogo obrazovaniia

SPIN RSCI: 5342-1373
Scopus AuthorID: 57147160800
ORCID: 0000-0003-3872-5923

Close metadata

References:

Diagnostic and Statistical Manual of mental disorders, fifth edition (DSM-V).
Rehabilitation of higher cortical functions in patients with focal brain damage. Clin. recommended. AN Bogolepova, et al. Moscow: MEDpress-inform, 2020;192. (In Russ.).
The incidence of the entire population of Russia in 2017. Statistical materials. Part I. M, 2018. (In Russ.). https://www.rosminzdrav.ru/ministry/61/22/stranitsa-979/statisticheskie-i-informatsionnye-materialy/statisticheskiy-sbornik-2017-god
Piradov MA, Maksimova MYu, Tanashyan MM. Stroke. Step-by-step instruction. GEOTAR Media, 2019. (In Russ.).
Zakharov VV. Cognitive impairment after a stroke: medical and social significance and approaches to therapy. Atmosphere. Nervous Diseases. 2015;2:2-8. (In Russ.).
Klimov LV, Parfenov VA. Cognitive impairment in the acute period of ischemic stroke. Nevrol. Zh. 2006;11(App. 1):53-56. (In Russ.)
Cherdak MA, Jahno NN. Neurodegenerative and vascular factors of post-stroke cognitive disorders. Nevrologicheskij zhurnal. 2012;5(17):10-15. (In Russ.)
Kulesh AA, Shestakov VV. Post-stroke cognitive impairment and the possibility of therapy with drug cellex. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2016;116(5):38-42. (In Russ.). https://doi.org/10.17116/jnevro20161165138-42
Bogolepova AN, Kovalenko EA. The dynamics of post-stroke cognitive deficit and the main factors that influence it. Pharmateka. 2018;5:358:Neurology 46-52. (In Russ.). https://doi.org/10.18565/pharmateca.2018.5.46-52
Verbitskaya SV, Parfenov VA. Clinical experience with memantine in post-stroke dementia. Nevrol. Zh. 2008;13 (4):45-49. (In Russ.).
Levin OS, Vasenina EE, Dudarova MA, Chimagomedova ASh. The deposited progress of cognitive disorders after ischemic stroke: causes and approaches to correction. Modern therapy in psychiatry and neurology. 2017;4:14-19. (In Russ.).
Renton T, Tibbles A, Topolovec-Vranic J Neurofeedback as a form of cognitive rehabilitation therapy following stroke: A systematic review. PLoS ONE. 2017;12(5):e0177290. https://doi.org/10.1371/journal.pone.0177290
Verbitskaya SV, Parfenov VA, Reshetnikov VA, Kozlov VV, Kabaeva AR. Post-stroke cognitive impairment (results of a 5-year follow-up). Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, neuropsychiatry, psychosomatics. 2018;10(1):37–42. (In Russ.). https://doi.org/10.14412/2074-2711-2018-1-37-42
Rohde D, Gaynor E, Large M, Mellon L, Hall P, Brewer L, Bennett K, Williams D, Dolan E, Callaly E, Hickey A. The Impact of Cognitive Impairment on Poststroke Outcomes: A 5-Year Follow-Up. J Geriatr Psychiatry Neurol. 2019 Sep;32(5):275-281. https://doi.org/10.1177/0891988719853044
Zakharova-Luneva E, Cooke DM, Okano S, Hurst C, Geffen S, Eagles R. The relationship between cognition and functional outcomes in rehabilitation: FIMCog vs. MoCA. Geriatr Gerontol Int. 2020 Feb 11. https://doi.org/10.1111/ggi.13884
Starchina YuA. Cognitive impairment after a stroke Medical Advice Neurology. 2017;27-32. (In Russ.). https://doi.org/10.21518/2079-701X-2017-0-27-32
Rostamian S, Mahinrad S, Stijnen T, Sabayan B, de Craen AJ. Cognitive impairment and risk of stroke: a systematic review and meta-analysis of prospective cohort studies. Stroke. 2014 May;45(5):1342-1348. https://doi.org/10.1161/STROKEAHA.114.004658
Rohde D, Gaynor E, Large M, Mellon L, Bennett K, Williams DJ, Brewer L, Hall P, Callaly E, Dolan E, Hickey A Cognitive impairment and medication adherence post-stroke: A five-year follow-up of the ASPIRE-S cohort. PLoS One. 2019 Oct 17;14(10):e0223997. https://doi.org/10.1371/journal.pone.0223997
Yakhno NN, Preobrazhenskaya IS, Zakharov VV, Stepkina DA, Lokshina AB, Mkhitaryan EA, Koberskaya NN, Savushkina IY. Prevalence of cognitive impairments in neurological diseases: Analysis of the activities of a specialized outpatient reception office. Neurology, Neuropsychiatry, Psychosomatics. 2012;4(2):30-35. (In Russ.). https://doi.org/10.14412/2074-2711-2012-378
Socially significant diseases of the Russian population in 2018 (Statistical materials). M, 2019. (In Russ.). http://www.rosminzdrav.ru/ministry/61/22/stranitsa-979/statisticheskie-i-informatsionnye-materialy/statisticheskiy-sbornik-2018-god
Prokopenko SV, Mozheiko EYu, Zubritskaya EM, Bezdenezhnykh AF. Correction of cognitive impairment in patients with craniocerebral trauma. Consilium Medicum. 2017;19(2.1):64-69. (In Russ.).
Zakharov VV, Drozdova EA. Cognitive impairments in patients with brain injury. Neurology, Neuropsychiatry, Psychosomatics. 2013;(4):88–93. https://doi.org/10.14412/2074-2711-2013-2462
Drozdova EA, Zakharov VV. Cognitive function in the acute period of cerebral commotion. Nevrologicheskiy zhurnal. 2012;9(2):15-20. (In Russ.).
Drozdova EA, Zakharov VV. Comparative analysis of cognitive impairments in the acute period of mild and moderate traumatic brain injury. Nevrologicheskiy zhurnal. 2012;17(6):12-18. (In Russ.).
Marquez de la Plata CD, Hart T, Hammond FM, Frol AB, Hudak A, Harper CR, O’Neil-Pirozzi TM, Whyte J, Carlile M, Diaz-Arrastia R. Impact of age on long-term recovery from traumatic brain injury. Arch Phys Med Rehabil. 2008;89(5):896-903. https://doi.org/10.1016/j.apmr.2007.12.030
Rohde A, Worrall L, Le Dorze G. Systematic review of the quality of clinical guidelines for aphasia in stroke management. J Eval Clin Pract. 2013;19:994-1003. https://doi.org/10.1111/jep.12023
Hilari K, Needle JJ, Harrison KL. What are the important factors in health-related quality of life for people with aphasia? A systematic review. Arch Phys Med Rehabil. 2012;93 1 Suppl:S86-95. https://doi.org/10.1016/j.apmr.2011.05.028
Lam JM, Wodchis WP. The relationship of 60 disease diagnoses and 15 conditions to preference-based health-related quality of life in Ontario hospital-based long-term care residents. Med Care. 2010;48(4):380-387. https://doi.org/10.1097/MLR.0b013e3181ca2647
Bakas T, Kroenke K, Plue LD, Perkins SM, Williams LS. Outcomes among family caregivers of aphasic versus nonaphasic stroke survivors. Rehabil Nurs. 2006;31(1):33-42.
Yu ZZ, Jiang SJ, Jia ZS, Xiao HY, Zhou MQ. Study on Language Rehabilitation for Aphasia. Chin Med J. 2017;130:1491-1497. https://doi.org/10.4103/0366-6999.207465
de Oliveira FF, Correia Marin Sde M, Ferreira Bertolucci PH. Communicating with the non-dominant hemisphere: Implications for neurological rehabilitation. Neural Regen Res. 2013;8:1236-1246. https://doi.org/10.3969/j.issn.1673-5374.2013.13.009
Shklovskii VM. Kontseptsiia neiroreabilitatsii bol’nykh s posledstviiami insul’ta. Zhurn. nevrologii i psikhiatrii im SS Korsakova. Insul’t. 2003;8:10-23. (In Russ.).
Cappa SF, Benke T, Clarke S, Rossi B, Stemmer B, van Heugten CM; EFNS guidelines on cognitive rehabilitation: report of an EFNS task force. European Journal of Neurology. 2005;12(9):665-680.
Cicerone KD, Dahlberg C, Kalmar K, Langenbahn DM, Malec JF, Bergquist TF, Felicetti T, Giacino JT, Harley JP, Harrington DE, Herzog J, Kneipp S, Laatsch L, Morse PA. Evidence-based cognitive rehabilitation: recommendations for clinical practice. Archives of Physical Medicine and Rehabilitation. 2000;81(12):1596-1615.
Kumar KS, Samuelkamaleshkumar S, Viswanathan A, Macaden AS, Cochrane Work Group. Cognitive rehabilitation for adults with traumatic brain injury to improve occupational outcomes. Cochrane Database Syst Rev. 2017 Jun 20;6:CD007935. https://doi.org/10.1002/14651858.CD007935.pub2
Koehler R, Wilhelm EE. Shoulson, Cognitive Rehabilitation Therapy for Traumatic Brain Injury: Evaluating the Evidence, National Academies Press, Washington, DC, 2011
Cappa SF, Benke T, Clarke S, Rossi B, Stemmer B, van Heugten CMV. Cognitive rehabilitation. In: Gilhus NE, Barnes MP, Brainin M. (eds). European Handbook of Neurological Management , Volume 1, 2st edn. Blackwell Publishing Ltd.; 2011;545-567.
Cicerone KD, Dahlberg C, Malec JF, Langenbahn DM, Felicetti T, Kneipp S, Ellmo W, Kalmar K, Giacino JT, Harley JP, Laatsch L, Morse PA, Catanese J. Evidencebased cognitive rehabilitation: updated review of the literature from 1998 through 2002. Arch Phys Med Rehabil. 2005;86:1681-1692. https://doi.org/10.1016/j.apmr.2005.03.024
Cicerone KD, Langenbahn DM, Braden C, Malec JF, Kalmar K, Fraas M, Felicetti T, Laatsch L, Harley JP, Bergquist T, Azulay J, Cantor J, Ashman T. Evidence-based cognitive rehabilitation: updated review of the literature from 2003 through 2008. Arch Phys Med Rehabil. 2011 Apr;92(4):519-530. https://doi.org/10.1016/j.apmr.2010.11.015
Hasanzadeh Pashang S, Zare H, Alipour A, Sharif-Alhoseini M. The effectiveness of cognitive rehabilitation in improving visual and auditory attention in ischemic stroke patients. Acta Neurol Belg. 2020 Feb 6. https://doi.org/10.1007/s13760-020-01288-4
Cicerone KD, Goldin Y, Ganci K, Rosenbaum A, Wethe JV, Langenbahn DM, Malec JF, Bergquist TF, Kingsley K, Nagele D, Trexler L, Fraas M, Bogdanova Y, Harley JP. Evidence-based cognitive rehabilitation: systematic review of the literature from 2009 through 2014. Arch Phys Med Rehabil. 2019 Aug;100(8):1515-1533. https://doi.org/10.1016/j.apmr.2019.02.011
Prokopenko SV, Dyadyuk TV, Mozheyko EYu, Bezdenezhnykh AF, Koryagina TD, Anay-Ool TS. Use of computer stimulating programs in patients with post-stroke cognitive impairment. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, neuropsychiatry, psychosomatics. 2017;9(3):48-53. https://doi.org/10.14412/2074-2711-2017-3-48-53
Maggio MG, De Luca R, Molonia F, Porcari B, Destro M, Casella C, Salvati R, Bramanti P, Calabro RS. Cognitive rehabilitation in patients with traumatic brain injury: A narrative review on the emerging use of virtual reality. J Clin Neurosci. 2019 Mar;61:1-4. https://doi.org/10.1016/j.jocn.2018.12.020
Messinis L, Kosmidis MH, Nasios G, Dardiotis E, Tsaousides Th. Cognitive Neurorehabilitation in Acquired Neurological Brain Injury. Behavioural Neurology. 2019;11:1-4.
Munsell M, De Oliveira E, Saxena S, Godlove J, Kiran S. Closing the Digital Divide in Speech, Language, and Cognitive Therapy: Cohort Study of the Factors Associated With Technology Usage for Rehabilitation. J Med Internet Res. 2020;22(2):e16286). https://doi.org/10.2196/16286
Sarfo FS, Ulasavets U, Opare-Sem OhK, Ovbiagele B. Tele-rehabilitation after stroke: an updated systematic review of the literature. J Stroke Cerebrovasc Dis. 2018;27(9):2306-2318. https://doi.org/10.1016/j.jstrokecerebrovasdis.2018.05.013
Stradecki-Cohan HM, Youbi M, Cohan CH, Saul I, Garvin AA, Perez E, Dave KR, Wright CB, Sacco RL, Perez-Pinzon MA. Physical Exercise Improves Cognitive Outcomes in 2 Models of Transient Cerebral Ischemia. Stroke. 2017 Aug;48(8):2306-2309. https://doi.org/10.1161/STROKEAHA.117.017296
Hsu CL, Best JR, Davis JC, Nagamatsu LS, Wang S, Boyd LA, Hsiung GR, Voss MW, Eng JJ, Liu-Ambrose T. Aerobic exercise promotes executive functions and impacts functional neural activity among older adults with vascular cognitive impairment. Br J Sports Med. 2017 Apr 21. pii: bjsports-2016-096846. https://doi.org/10.1136/bjsports-2016-096846
Zheng G, Zhou W, Xia R, Tao J, Chen L. Aerobic Exercises for Cognition Rehabilitation following Stroke: A Systematic Review. J Stroke Cerebrovasc Dis. 2016 Nov;25(11):2780-2789. https://doi.org/10.1016/j.jstrokecerebrovasdis.2016.07.035
Buccellato KH, Nordstrom M, Murphy JM, Burdea GC, Polistico K, House G, Kim N, Grampurohit N, Sorensen J, Isaacson BM, Pasquina PF. A Randomized Feasibility Trial of a Novel, Integrative, and Intensive Virtual Rehabilitation Program for Service Members Post-Acquired Brain Injury. Mil Med. 2020 Feb 12;185(1-2):e203-e211. https://doi.org/10.1093/milmed/usz150
Maggio MG, Torrisi M, Buda A, De Luca R, Piazzitta D, Cannavò A, Leo A, Milardi D, Manuli A, Calabro RS. Effects of robotic neurorehabilitation through lokomat plus virtual reality on cognitive function in patients with traumatic brain injury: A retrospective case-control study. Int J Neurosci. 2020 Feb;130(2):117-123. https://doi.org/10.1080/00207454.2019.1664519
Naumenko AA, Gromova DO, Preobrazhenskaya IS. Cognitive training and rehabilitation of patients with cognitive impairment. Doctor.ru Medical Rehabilitation. 2017;11(140):31-38. (In Russ.).
Bherer L. Cognitive plasticity in older adults: effects of cognitive training and physical exercise. Ann. NY Acad. Sci. 2015;1337:1-6. https://doi.org/10.1111/nyas.12682
Bogolepova AN, Chukanova EI. The problem of neuroplasticity in modern neurology. Journal of Neurology and Psychiatry SS Korsakova. 2010;110(8):72-75. (In Russ.).
Hartbauer M, Hutter-Paie B, Windisch M. Effects of Cerebrolysin on the outgrowth and protection of processes of cultured brain neurons. J Neural Transm (Vienna, Austria: 1996). 2001;108(5):581-592.
Hanson LR, Liu XF, Ross TM, Doppler E, Zimmermann-Meinzingen S, Moessler H, Frey WH. Cerebrolysin reduces infarct volume in a rat model of focal cerebral ischemic damage. Am J Neuroprotec Neuroregen. 2009;1(1):60-66. https://doi.org/10.1166/ajnn.2009.1010
Zhang L, Chopp M, Lu M, Zhang T, Winter S, Doppler E, Meier D, Chao L, Eapen A, Pabla P, Gang Zhang Z. Cerebrolysin dose-dependently improves neurological outcome in rats after acute stroke: A prospective, randomized, blinded, and placebo-controlled study. International Journal of Stroke. 2016 Apr;11(3):347-355. https://doi.org/10.1177/1747493015625645
Bogolepova AN. Possibilities of neurotrophic therapy in early recovery after stroke. S.S. Korsakov Journal of Neurology and Psychiatry = Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova. 2019;119(8 vyp 2):74-79. (In Russ.). https://doi.org/10.17116/jnevro201911908284
Chukanova EI, Gusev EI, Belousov DYu, Repyev AP, Belousov YuB. Results of multicenter randomized controlled clinical-economic study of therapy of acute ischemic stroke with Cerebrolysin. Good Clinical Practice. 2011;3:14-37. (In Russ.)
Chang WH, Park CH, Kim DY, Shin YI, Ko MH, Lee A, Jang SY, Kim YH. Cerebrolysin combined with rehabilitation promotes motor recovery in patients with severe motor impairment after stroke. BMC Neurol. 2016;16:31. https://doi.org/10.1186/s12883-016-0553-z
Muresanu DF, Heiss WD, Hoemberg V, Bajenaru O, Popescu CD, Vester JC, Rahlfs VW, Doppler E, Meier D, Moessler H, Guekht A. Cerebrolysin and Recovery After Stroke (CARS): A Randomized, Placebo-Controlled, Double-Blind, Multicenter Trial. Stroke. 2016;47(1):151-159. https://doi.org/10.1161/STROKEAHA.115.009416
Muresanu DF, Florian S, Hömberg V, Matula C, von Steinbüchel N, Vos PE, von Wild K, Birle C, Muresanu I, Slavoaca D, Rosu OV, Strilciuc S, Vester J. Efficacy and safety of cerebrolysin in neurorecovery after moderate-severe traumatic brain injury: results from the CAPTAIN II trial. Neurol Sci. 2020; 12: 45-49. https://doi.org/10.1007/s10072-019-04181-y
Poon W, Matula C, Vos PE, Muresanu DF, von Steinbüchel N, von Wild K, Hömberg V, Wang E, Lee TMC, Strilciuc S, Vester JC. Safety and efficacy of Cerebrolysin in acute brain injury and neurorecovery: CAPTAIN I-a randomized, placebo-controlled, double-blind, Asian-Pacific trial. Neurol Sci. 2020 Feb;41(2):281-293. https://doi.org/10.1007/s10072-019-04053-5