Treatment of contusion of moderate severity in children in outpatient clinics

Skripnik O.Yu.; Sumenko V.V.; Trusova O.Yu.; Danilova E.I.; Evstifeeva G.Yu.; Chelpachenko O.E.

doi:https://doi.org/10.17116/jnevro202012003129

Skripnik O.Yu.

City Clinical Hospital No. 5, Orenburg, Children’s Polyclinic No.10, Orenburg, Russia

Sumenko V.V.

Orenburg State Medical University, Ministry of Health, 6 Sovetskaya St., Orenburg, Russian Federation, 460000

Trusova O.Yu.

Orenburg State Medical University, Orenburg, Russia

Danilova E.I.

Orenburg State Medical University, Orenburg, Russia

Evstifeeva G.Yu.

City Clinical Hospital No. 5, Orenburg, Children’s Polyclinic No.10, Orenburg, Russia

Chelpachenko O.E.

Institute of Cellular and Intracellular Symbiosis, Ural Branch of RAS, Orenburg, Russia

Treatment of contusion of moderate severity in children in outpatient clinics

Authors:

Skripnik O.Yu., Sumenko V.V., Trusova O.Yu., Danilova E.I., Evstifeeva G.Yu., Chelpachenko O.E.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(3): 29‑33

DOI: 10.17116/jnevro202012003129

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To cite this article:

Skripnik OYu, Sumenko VV, Trusova OYu, Danilova EI, Evstifeeva GYu, Chelpachenko OE. Treatment of contusion of moderate severity in children in outpatient clinics. S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(3):29‑33. (In Russ.)
https://doi.org/10.17116/jnevro202012003129

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

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Abstract:

Objective. To determine the efficacy of cortexin in treatment of traumatic brain injuries with contusion of moderate severity in children in an outpatient clinics. Materials and methods. Seventy-four patients, aged 6–13 years, with a traumatic brain injury and a moderate brain contusion were examined. A comprehensive clinical examination, including neurological and ophthalmological examinations, EEG, brain CT scan, testing using a set of experimental psychological techniques, was performed. Children of the main group received standard therapy and cortexin. Children of the control group received similar treatment without cortexin. Re-examination was carried out 30 days after the start of treatment. Results. After the treatment, a positive dynamics was noted in both groups. There were a decrease in the severity of subjective symptoms (p<0,01) and focal neurological symptoms (p <0,001) as well as absence of acute waves to physical activity according to EEG results in the main group compared with the control group. Also, EEG showed that cortical electrogenesis corresponded to the age of the patient, hypertensive/hydrocephalic signs were stopped (p <0,05), positive changes in cognitive functions occurred. Conclusion. The study showed the positive dynamics in the recovery of cognitive functions, the normalization of EEG parameters and stopping of hypertension-hydrocephalic symptoms in children with traumatic brain injuries with contusion of moderate severity a month after the start of treatment with cortexin.

Keywords:

head injuries

children

treatment

cortexin

Authors:

Skripnik O.Yu.

City Clinical Hospital No. 5, Orenburg, Children’s Polyclinic No.10, Orenburg, Russia

Sumenko V.V.

Orenburg State Medical University, Ministry of Health, 6 Sovetskaya St., Orenburg, Russian Federation, 460000

Trusova O.Yu.

Orenburg State Medical University, Orenburg, Russia

Danilova E.I.

Orenburg State Medical University, Orenburg, Russia

Evstifeeva G.Yu.

City Clinical Hospital No. 5, Orenburg, Children’s Polyclinic No.10, Orenburg, Russia

Chelpachenko O.E.

Institute of Cellular and Intracellular Symbiosis, Ural Branch of RAS, Orenburg, Russia

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