A prognostic model of cognitive impairment in patients with type 1 diabetes mellitus

Samoĭlova Iu.G.; Rotkank M.A.; Kudlay D.A.; Zhukova N.G.; Matveeva M.V.; Tolmachev I.V.

doi:https://doi.org/10.17116/jnevro202012003119

Samoĭlova Iu.G.

GBOU VPO "Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet" Minzdrava RF, Tomsk

Rotkank M.A.

Siberian State Medical University, Tomsk, Russia

Kudlay D.A.

Institute for Advanced Studies of the Federal Medical and Biological Agency, Moscow, Russia

Zhukova N.G.

Siberian State Medical University, Tomsk, Russia

SPIN RSCI: 6982-5313
Scopus AuthorID: 56452586900
ORCID: 0000-0001-6547-6622

Matveeva M.V.

Siberian State Medical University, Tomsk, Russia

Tolmachev I.V.

Siberian State Medical University, Tomsk, Russia

A prognostic model of cognitive impairment in patients with type 1 diabetes mellitus

Authors:

Samoĭlova Iu.G., Rotkank M.A., Kudlay D.A., Zhukova N.G., Matveeva M.V., Tolmachev I.V.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(3): 19‑22

DOI: 10.17116/jnevro202012003119

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To cite this article:

Samoĭlova IuG, Rotkank MA, Kudlay DA, Zhukova NG, Matveeva MV, Tolmachev IV. A prognostic model of cognitive impairment in patients with type 1 diabetes mellitus. S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(3):19‑22. (In Russ.)
https://doi.org/10.17116/jnevro202012003119

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

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Abstract:

Objective. To develop a model for the prognosis of cognitive impairment in patients with type 1 diabetes mellitus based on data from proton magnetic resonance spectroscopy. Materials and methods. Patients with type 1 diabetes mellitus and individuals without diabetes were examined (control group). All participants were evaluated for carbohydrate metabolism, underwent neuropsychological testing (MoCa test), proton magnetic resonance spectroscopy of the brain. Statistical processing of the results was performed using the IBM SPSS Statistics 20.0 program. The predictive model is calculated using discriminant analysis. Results. Based on the data of proton magnetic resonance spectroscopy, a predictive model for the development of cognitive impairment in patients with type 1 diabetes mellitus was obtained using discriminant analysis. Conclusions. The method for the early diagnosis of cognitive impairment allows predicting the development of cognitive dysfunction in patients with type 1 diabetes in the early stages and can be used in clinical practice to assess the effectiveness of preventive therapy for cognitive impairment.

Keywords:

cognitive impairments

diabetes mellitus

magnetic resonance spectroscopy

prognostic model

Authors:

Samoĭlova Iu.G.

GBOU VPO "Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet" Minzdrava RF, Tomsk

Rotkank M.A.

Siberian State Medical University, Tomsk, Russia

Kudlay D.A.

Institute for Advanced Studies of the Federal Medical and Biological Agency, Moscow, Russia

Zhukova N.G.

Siberian State Medical University, Tomsk, Russia

SPIN RSCI: 6982-5313
Scopus AuthorID: 56452586900
ORCID: 0000-0001-6547-6622

Matveeva M.V.

Siberian State Medical University, Tomsk, Russia

Tolmachev I.V.

Siberian State Medical University, Tomsk, Russia

Close metadata

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