Transcranial magnetic stimulation in the diagnostic and treatment of pain syndromes in children and adults

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The authors review the literature and own data concerning therapeutic use of transcranial magnetic stimulation (TMS) in children and adult patients with pain syndromes of different origins. TMS may act as a tool to excite or inhibit neuroplasticity in the central nervous system, which depends of the therapeutic regime used. TMS induces neurogenesis and synaptogenesis, rhythmic TMS may cause long-lasting after-effects, including pain inhibitory effect. A decrease in the threshold and an increase in the amplitude of motor evoked potentials in TMS are the most frequent changes in pain syndromes in the diagnostic modality. The efficacy of different regimes in the treatment of pain syndromes remains understudied. Despite vast knowledge on clinical use of TMS in pain syndromes in adults, in pediatrics its use is limited to migraine treatment. TMS is a valuable diagnostic and therapeutic tool that should be more often implemented in neurorehabilitation and treatment of neurological diseases in adults and children with pain syndromes.

Keywords:

transcranial magnetic stimulation

neuroplasticity

pain

children

neurorehabilitation

Authors:

Voitenkov V.B.

Pediatric Research and Clinical Center for Infectious Diseases, Saint Petersburg, Russia

SPIN RSCI: 6190-6930
Scopus AuthorID: 55797978400
ORCID: 0000-0003-0448-7402

Ekusheva E.V.

Otdel patologii vegetativnoĭ nervnoĭ sistemy Nauchno-issledovatel'skogo tsentra Pervogo Moskovskogo gosudarstvennogo meditsinskogo universiteta im. I.M. Sechenova, Moskva

SPIN RSCI: 8828-0015
Scopus AuthorID: 6507964640
ORCID: 0000-0002-3638-6094

Skripchenko N.V.

Pediatric Research and Clinical Center for Infectious Diseases, Saint Petersburg, Russia

Damulin I.V.

kafedra nervnykh bolezneĭ Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova

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