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Tyuvina N.A.

Kafedra psikhiatrii i meditsinskoĭ psikhologii Pervogo Moskovskogo gosudarstvennogo universiteta im. I.M. Sechenova, Moskva

Stolyarova A.E.

Sechenov First Moscow State Medical University, Moscow, Russia

Smirnova V.N.

Kafedra psikhiatrii i meditsinskoĭ psikhologii Pervogo Moskovskogo gosudarstvennogo universiteta im. I.M. Sechenova, Moskva

Bipolar affective disorder: gender differences in the course and treatment

Authors:

Tyuvina N.A., Stolyarova A.E., Smirnova V.N.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2019;119(12): 162‑169

DOI: 10.17116/jnevro2019119121162

Read: 27760 times

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Table of contents

BIPOLAR AFFECTIVE DISORDER: GENDER DIFFERENCES IN THE COURSE AND TREATMENT
BIPOLAR AFFECTIVE DISORDER: GENDER DIFFERENCES IN THE COURSE AND TREATMENT

To cite this article:

Tyuvina NA, Stolyarova AE, Smirnova VN. Bipolar affective disorder: gender differences in the course and treatment. S.S. Korsakov Journal of Neurology and Psychiatry. 2019;119(12):162‑169. (In Russ.)
https://doi.org/10.17116/jnevro2019119121162

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
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Abstract:

Bipolar affective disorder (BAD) according to the latest international classifications (ICD-10, DSM-5) is recognized as its own disease, characterized by episodes of mania (or hypomania), hyperthymic personality and (or) a genetic predisposition to BAR in contrast to recurrent depressive disorder (RD). The history of development and classification of manic depressive disorder (MDD), difficulties of differential diagnosis between BAD and RD are presented in this literature review. It considers the clinical features of the course of BAR in men and women and also gender-specific therapy. Gender differences in the clinical picture, course and treatment of BAD are discussed. Attention is drawn to the differences in effectiveness and tolerability of antidepressants in men and women. It is concluded that identifying the gender particularities is important for treatment and prevention optimization.

Keywords:

bipolar affective disorder
recurrent depressive disorder
depression
gender differences
antidepressants

Authors:

Tyuvina N.A.

Kafedra psikhiatrii i meditsinskoĭ psikhologii Pervogo Moskovskogo gosudarstvennogo universiteta im. I.M. Sechenova, Moskva

Stolyarova A.E.

Sechenov First Moscow State Medical University, Moscow, Russia

Smirnova V.N.

Kafedra psikhiatrii i meditsinskoĭ psikhologii Pervogo Moskovskogo gosudarstvennogo universiteta im. I.M. Sechenova, Moskva

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