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Ivanova S.A.

Nauchno-issledovatel'skiĭ institut psikhicheskogo zdorov'ia Sibirskogo otdeleniia Rossiĭskoĭ akademii meditsinskikh nauk, Tomsk

Alifirova V.M.

Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Tomsk, Russia

Zhukova I.A.Жукова Ирина Александровна

Siberian State Medical University, Tomsk

Boyko A.S.

Mental Health Research Institute, Tomsk

Fedorenko O.Iu.

Nauchno-issledovatel'skiĭ institut psikhicheskogo zdorov'ia Sibirskogo otdeleniia Rossiĭskoĭ akademii meditsinskikh nauk, Tomsk;
Natsional'nyĭ issledovatel'skiĭ Tomskiĭ politekhnicheskiĭ universitet, Tomsk

Zhukova N.G.

Siberian State Medical University, Tomsk, Russia

Bokhan N.A.

Nauchno-issledovatel'skiĭ institut psikhicheskogo zdorov'ia Tomskogo nauchnogo tsentra Sibirskogo otdeleniia RAMN

The association of the DRD3 gene with Parkinson’s disease

Authors:

Ivanova S.A., Alifirova V.M., Zhukova I.A.Жукова Ирина Александровна, Boyko A.S., Fedorenko O.Iu., Zhukova N.G., Bokhan N.A.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2016;116(5): 71‑74

DOI: 10.17116/jnevro20161165171-74

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Table of contents

THE ASSOCIATION OF THE DRD3 GENE WITH PARKINSON’S DISEASE
THE ASSOCIATION OF THE DRD3 GENE WITH PARKINSON’S DISEASE

To cite this article:

Ivanova SA, Alifirova VM, Zhukova IAЖукова Ирина Александровна, Boyko AS, Fedorenko OIu, Zhukova NG, Bokhan NA. The association of the DRD3 gene with Parkinson’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2016;116(5):71‑74. (In Russ.)
https://doi.org/10.17116/jnevro20161165171-74

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
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Abstract:

Objective. To investigate the association between dopamine receptor DRD3 gene tag single nucleotide polymorphisms (SNPs) and the risk of Parkinson’s disease (PD). Material and methods. One hundred and forty-three patients with PD and 96 healthy individuals from the Russian population were examined. Ten tag SNPs (rs963468, rs2134655, rs9817063, rs324035, rs11721264, rs1800828, rs3773678, rs167770, rs167771, rs7633291) within DRD3 have been genotyped. Results and conclusion. Associations between 4 polymorphisms (rs11721264, rs3773678, rs167771, rs324035) and PD have been found. Our study confirms the involvement of polymorphic features of dopamine receptors genes in the pathophysiology in PD.

Keywords:

Parkinson’s disease
tag single nucleotide polymorphisms
gene DRD3

Authors:

Ivanova S.A.

Nauchno-issledovatel'skiĭ institut psikhicheskogo zdorov'ia Sibirskogo otdeleniia Rossiĭskoĭ akademii meditsinskikh nauk, Tomsk

Alifirova V.M.

Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Tomsk, Russia

Zhukova I.A.Жукова Ирина Александровна

Siberian State Medical University, Tomsk

Boyko A.S.

Mental Health Research Institute, Tomsk

Fedorenko O.Iu.

Nauchno-issledovatel'skiĭ institut psikhicheskogo zdorov'ia Sibirskogo otdeleniia Rossiĭskoĭ akademii meditsinskikh nauk, Tomsk;
Natsional'nyĭ issledovatel'skiĭ Tomskiĭ politekhnicheskiĭ universitet, Tomsk

Zhukova N.G.

Siberian State Medical University, Tomsk, Russia

Bokhan N.A.

Nauchno-issledovatel'skiĭ institut psikhicheskogo zdorov'ia Tomskogo nauchnogo tsentra Sibirskogo otdeleniia RAMN

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References:

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