Objective. An influence of L-lysine aescinat on decrease of pain syndrome and normalization of movement's functions. Material and methods. 220 patients with dorsalgia has been studied. To asses treatment efficacy the Huskisson's visual analog scale, multidimensional verbal and color test of pain and the modified Waddel's scale were used. Results and conclusion. The results of the study revealed that the use of L-lysine aescinat promotes considerable acceleration of process of regression of a pain syndrome and the efficacious rehabilitation of movements and plays a significant role in faster and expressed knocking over of a radicular syndrome.