Authors studied 192 patients with migraine, tension-type headache (TTH) and cluster headache (CH). Active muscle trigger points (MTrP) were found at 84.2% migraineurs, 97.6% patients with TTH and at 100% patient with CH. MTrP were frequently found in the splenius muscle of head (96.8%), trapezius muscle (86.5%) and splenius muscle of neck (83.8%). Pressure to the MTrP at the trapezius muscle or splenius muscle of head caused the blood flow velocity (BFV) increase in the medial cerebral artery (MCA) and the Lindegaard ratio (LR) elevation within the range of 2 to 3 (a feature of functional vasoconstriction). The increase of BFV in MCA and LR in patients with primary headaches with active MTrP before treatment and the normalization of these values (BFV in MCA and LR) after treatment are evidence of MTrP influence on the cerebral arteries tone.