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Gavrilova S.I.

Otdel po izucheniiu bolezni Al'tsgeĭmera i assotsiirovannykh s neĭ rasstroĭstv Nauchnogo tsentra psikhicheskogo zdorov'ia RAMN, Moskva

Kolykhalov I.V.

Otdel po izucheniiu bolezni Al'tsgeĭmera i assotsiirovannykh s neĭ rasstroĭstv Nauchnogo tsentra psikhicheskogo zdorov'ia RAMN, Moskva

Fedorova Ia.B.

Otdel po izucheniiu bolezni Al'tsgeĭmera i assotsiirovannykh s neĭ rasstroĭstv Nauchnogo tsentra psikhicheskogo zdorov'ia RAMN, Moskva

Kalyn Ia.B.

Otdel po izucheniiu bolezni Al'tsgeĭmera i assotsiirovannykh s neĭ rasstroĭstv Nauchnogo tsentra psikhicheskogo zdorov'ia RAMN, Moskva

Selezneva N.D.

Otdel po izucheniiu bolezni Al'tsgeĭmera i assotsiirovannykh s neĭ rasstroĭstv Nauchnogo tsentra psikhicheskogo zdorov'ia RAMN, Moskva

Samorodov A.V.

Moskovskiĭ gosudarstvennyĭ tekhnicheskiĭ universitet im. N.. Baumana, Moskva

Miasoedov S.N.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva

Boksha I.S.

Research Centre of Mental Health

Prognosis of cognitive deficit progression in aged patients with mild cognitive impairment under prolonged therapy (a three year observation)

Authors:

Gavrilova S.I., Kolykhalov I.V., Fedorova Ia.B., Kalyn Ia.B., Selezneva N.D., Samorodov A.V., Miasoedov S.N., Boksha I.S.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2013;113(3): 45‑53

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Table of contents

PROGNOSIS OF COGNITIVE DEFICIT PROGRESSION IN AGED PATIENTS WITH MILD COGNITIVE IMPAIRMENT UNDER PROLONGED THERAPY (A THREE YEAR OBSERVATION)
PROGNOSIS OF COGNITIVE DEFICIT PROGRESSION IN AGED PATIENTS WITH MILD COGNITIVE IMPAIRMENT UNDER PROLONGED THERAPY (A THREE YEAR OBSERVATION)

To cite this article:

Gavrilova SI, Kolykhalov IV, Fedorova IaB, et al. Prognosis of cognitive deficit progression in aged patients with mild cognitive impairment under prolonged therapy (a three year observation). S.S. Korsakov Journal of Neurology and Psychiatry. 2013;113(3):45‑53. (In Russ.)

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
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Abstract:

The aim of the study was to predict treatment efficacy in patients with mild cognitive impairment (MCI) and to find the most reliable clinical tests for the prediction of dementia. Patients with amnestic MCI (n=53) were treated with cerebrolysin for three years and underwent regularly neurocognitive and clinical psychiatric tests. The data were analyzed using non-parametric statistics, cluster analysis, and linear discriminate analysis. The combination of statistical methods has enabled to predict the degree of cognitive impairment as well as the development of dementia. A "dementia risk group" with fast cognitive decline (i.e. the low efficacy of the treatment) was identified. The tests are ranked according to their predictive values.

Keywords:

mild cognitive impairmen
dementia
prognosis
statistical methods

Authors:

Gavrilova S.I.

Otdel po izucheniiu bolezni Al'tsgeĭmera i assotsiirovannykh s neĭ rasstroĭstv Nauchnogo tsentra psikhicheskogo zdorov'ia RAMN, Moskva

Kolykhalov I.V.

Otdel po izucheniiu bolezni Al'tsgeĭmera i assotsiirovannykh s neĭ rasstroĭstv Nauchnogo tsentra psikhicheskogo zdorov'ia RAMN, Moskva

Fedorova Ia.B.

Otdel po izucheniiu bolezni Al'tsgeĭmera i assotsiirovannykh s neĭ rasstroĭstv Nauchnogo tsentra psikhicheskogo zdorov'ia RAMN, Moskva

Kalyn Ia.B.

Otdel po izucheniiu bolezni Al'tsgeĭmera i assotsiirovannykh s neĭ rasstroĭstv Nauchnogo tsentra psikhicheskogo zdorov'ia RAMN, Moskva

Selezneva N.D.

Otdel po izucheniiu bolezni Al'tsgeĭmera i assotsiirovannykh s neĭ rasstroĭstv Nauchnogo tsentra psikhicheskogo zdorov'ia RAMN, Moskva

Samorodov A.V.

Moskovskiĭ gosudarstvennyĭ tekhnicheskiĭ universitet im. N.. Baumana, Moskva

Miasoedov S.N.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva

Boksha I.S.

Research Centre of Mental Health

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