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Tret'iakova E.A.

Permskaia gosudarstvennaia meditsinskaia akademiia im. akad. E.A. Vagnera

Karakulova Iu.V.

Kafedra nevrologii lechebnogo fakul'teta im. prof. V.P. Pervushina Permskoĭ gosudarstvennoĭ meditsinskoĭ akademii im. akad. E.A. Vagnera

Clinical and biochemical mechanisms of the formation of chronic low back pain

Authors:

Tret'iakova E.A., Karakulova Iu.V.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2011;111(9): 58‑60

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Table of contents

CLINICAL AND BIOCHEMICAL MECHANISMS OF THE FORMATION OF CHRONIC LOW BACK PAIN
CLINICAL AND BIOCHEMICAL MECHANISMS OF THE FORMATION OF CHRONIC LOW BACK PAIN

To cite this article:

Tret'iakova EA, Karakulova IuV. Clinical and biochemical mechanisms of the formation of chronic low back pain. S.S. Korsakov Journal of Neurology and Psychiatry. 2011;111(9):58‑60. (In Russ.)

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
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Abstract:

A comprehensive survey of 78 patients with chronic vertebral low back pain was conducted. Among them were 23 (29,5%) patients with radiculopathy and 55 (70,5%) patients with reflex syndromes without exacerbations. It was shown that patients with compressive syndromes of lumbar dorsopathy were characterized by the high intensity of pain, pronounced neuropathic pain component, lower quality of life as well as the significantly low serum serotonin content that was correlated with the degree of neuropathic pain severity and depression level.

Keywords:

chronic low back pain
radiculopathy
reflex syndrome
lumbar dorsopathy
serotonin
neuropathic pain

Authors:

Tret'iakova E.A.

Permskaia gosudarstvennaia meditsinskaia akademiia im. akad. E.A. Vagnera

Karakulova Iu.V.

Kafedra nevrologii lechebnogo fakul'teta im. prof. V.P. Pervushina Permskoĭ gosudarstvennoĭ meditsinskoĭ akademii im. akad. E.A. Vagnera

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References:

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  3. Karakulova Yu.V. Serotoninovaya sistema perifericheskoi krovi bol'nykh golovnoi bol'yu napryazheniya (kliniko-biokhimicheskoe issledovanie): Avtoref. dis. … d-ra med. nauk. Perm' 2006; 209.
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