Control of neuropathic pain in lumbosacral dorsalgia

Andreev V.V.

doi:https://doi.org/10.17116/jnevro2024124111152

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Abstract:

The literature sources devoted to the problem of the formation of neuropathic pain in lumbosacral dorsalgia and the effective treatment regimens used are analyzed. The clinical and pathogenetic justification of the appointment of complex drug treatment is presented, taking into account the most significant causes of acute and chronic nonspecific back pain — radicular, facet, musculotonic syndromes. It has been shown that the most effective drugs are antiepileptic drugs, nonsteroidal anti-inflammatory drugs, muscle relaxants of central prologued action. It has been shown that the intensity of neuropathic pain decreases with the administration of pregabalin. In acute nonspecific back pain, the use of aceclofenac is effective. The severity of musculotonic pain syndrome is significantly reduced when using tolperizone (Midocalm-long). The results of the analyzed studies confirm the effectiveness and safety of the combination.

Keywords:

nonspecific back pain

radiculopathy

musculotonic pain

facet syndrome

dorsalgia

aceclofenac

tolperizone

gabapentin

Authors:

Andreev V.V.

Academian I.P. Pavlov First Saint Petersburg State Medical University

ORCID: 0000-0003-2578-5783

Received:

24.10.2024

Accepted:

07.11.2024

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References:

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