Modern and promising therapies for postherpetic neuralgia

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Postherpetic neuralgia (PHN) is highly prevalent among the elderly and immunocompromised patients and decreases patients’ quality of life. Currently, much attention is paid to the prevention of this disease and the development of new therapies and treatment approaches. The article discusses new targets for treating this type of pain, both pharmacotherapy and invasive methods. Analysis of clinical trials shows that a combination of different therapies can improve symptom management and patients’ quality of life. It was shown that the earlier the treatment of PHN begins, the higher the probability of gaining control over the pain severity. The article emphasizes the need for further research to optimize approaches to PHN treatment and raise the medical community’s awareness about new treatment options.

Keywords:

shingles

herpes

postherpetic neuralgia

neuropathic pain

treatment of neuropathic neuralgia

Authors:

Dobrosmyslova A.O.

Federal Siberian Research Clinical Center

ORCID: 0000-0003-2523-9758

Khinovker V.V.

Federal Siberian Research Clinical Center;
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University

ORCID: 0000-0002-3162-6298

Koriachkin V.A.

St. Petersburg State Paediatric Medical University;
Turner National Medical Research Center for Paediatric Traumatology and Orthopedics

ORCID: 0000-0002-3400-8989

Pokhabov D.V.

Federal Siberian Scientific and Clinical Center

ORCID: 0000-0001-5895-5043

Received:

26.11.2024

Accepted:

27.12.2024

List of references:

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