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Sivkova S.N.

Detskaia gorodskaia bol'nitsa #8, Kazan';
Rossiĭskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. N.I. Pirogova, Moskva

Mukhin K.Iu.

Kafedra nervnykh bolezneĭ pediatricheskogo fakul'teta s kursom fakul'teta usovershenstvovaniia vracheĭ Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Moskva

Zaĭkova F.M.

Efficacy of treatment of focal forms of epilepsy in children with antiepileptic drugs of different generations

Authors:

Sivkova S.N., Mukhin K.Iu., Zaĭkova F.M.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2011;111(6): 42‑48

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EFFICACY OF TREATMENT OF FOCAL FORMS OF EPILEPSY IN CHILDREN WITH ANTIEPILEPTIC DRUGS OF DIFFERENT GENERATIONS
EFFICACY OF TREATMENT OF FOCAL FORMS OF EPILEPSY IN CHILDREN WITH ANTIEPILEPTIC DRUGS OF DIFFERENT GENERATIONS

To cite this article:

Sivkova SN, Mukhin KIu, Zaĭkova FM. Efficacy of treatment of focal forms of epilepsy in children with antiepileptic drugs of different generations. S.S. Korsakov Journal of Neurology and Psychiatry. 2011;111(6):42‑48. (In Russ.)

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An aim was to study the efficacy of different groups of antiepileptic drugs in the treatment of focal symptomatic (or probably symptomatic) epilepsy in children. The study included 96 patients, aged from 1 month to 17 years, 55 boys and 41 girls. They were stratified into three groups by drug type: group 1 (34 patients) was treated with phenobarbital, group 2 (31 patients) received topiramate and group 3 (31 patients) received lamotrigine. It has been shown that antiepileptic drugs of the new generation have higher efficacy with regard to focal forms of epilepsy in children compared to phenobarbital. However therapeutic effect, especially regarding seizure frequency, was specific for each drug.

Keywords:

epilepsy
focal symptomatic form
treatment
antiepileptic drugs of different groups

Authors:

Sivkova S.N.

Detskaia gorodskaia bol'nitsa #8, Kazan';
Rossiĭskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. N.I. Pirogova, Moskva

Mukhin K.Iu.

Kafedra nervnykh bolezneĭ pediatricheskogo fakul'teta s kursom fakul'teta usovershenstvovaniia vracheĭ Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Moskva

Zaĭkova F.M.

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