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Aleksandrova E.V.

NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

Zaĭtsev O.S.

NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

Tenedieva V.D.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Potapov A.A.

NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

Zakharova N.E.

NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

Kravchuk A.D.

NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

Oshorov A.V.

NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

Sokolova E.Iu.

NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

Shukhraĭ V.A.

Vorob'ev Iu.V.

Plasma catecholamines in consciousness recovery in patients with severe traumatic brain injury

Authors:

Aleksandrova E.V., Zaĭtsev O.S., Tenedieva V.D., Potapov A.A., Zakharova N.E., Kravchuk A.D., Oshorov A.V., Sokolova E.Iu., Shukhraĭ V.A., Vorob'ev Iu.V.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2011;111(3): 58‑63

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Table of contents

PLASMA CATECHOLAMINES IN CONSCIOUSNESS RECOVERY IN PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY
PLASMA CATECHOLAMINES IN CONSCIOUSNESS RECOVERY IN PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY

To cite this article:

Aleksandrova EV, Zaĭtsev OS, Tenedieva VD, et al. . Plasma catecholamines in consciousness recovery in patients with severe traumatic brain injury. S.S. Korsakov Journal of Neurology and Psychiatry. 2011;111(3):58‑63. (In Russ.)

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Changes in plasma noradrenalin (NA) and dopamine (DA) levels were evaluated in the stages of consciousness recovery in patients with severe traumatic brain injury with and without deep brain structure damage. Forty-eight patients (36 men and 12 women), aged from 12 to 56 (31,9±10,9) yeas, were enrolled in the study. Two variants of catecholamine (CA) changes were found: 1) a CA-dissociation that was oppositely directed to NA and DA changes was observed in unconsciousness; 2) a CA-dissociation (unidirectional NA and DA changes) that was observed after the restoration of consciousness. In patients with the damage of two frontal lobes and deep brain structures, CA-association periods were seen in the stage of mental confusion with psychomotor agitation or when the brain stem was damaged. The duration of CA-association was negatively correlated with the velocity, quality of consciousness recovery and outcomes evaluated by the Glasgow scale.

Keywords:

unconsciousness states
catecholamines
traumatic brain injury

Authors:

Aleksandrova E.V.

NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

Zaĭtsev O.S.

NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

Tenedieva V.D.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Potapov A.A.

NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

Zakharova N.E.

NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

Kravchuk A.D.

NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

Oshorov A.V.

NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

Sokolova E.Iu.

NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

Shukhraĭ V.A.

Vorob'ev Iu.V.

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