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Koltsov I.A.
Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies
Shchukin I.A.
Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies
Boiko A.N.
Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies
Posterior reversible encephalopathy syndrome in autoimmune disorders
Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(7‑2): 50‑57
Views: 861
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To cite this article:
Koltsov IA, Shchukin IA, Fidler MS, Yasamanova AN, Aryasova IK, Boiko AN. Posterior reversible encephalopathy syndrome in autoimmune disorders. S.S. Korsakov Journal of Neurology and Psychiatry.
2024;124(7‑2):50‑57. (In Russ.)
https://doi.org/10.17116/jnevro202412407250
Posterior reversible encephalopathy syndrome (PRES) is characterized by nonspecific symptoms, including not only pronounced non-focal and various focal neurological signs but also specific neuroimaging features, including vasogenic edema affecting predominantly the posterior area. PRES usually develops in the setting of acute arterial hypertension. However, it is not uncommon for PRES to develop in non-hypertensive patients, including people with autoimmune disorders (multiple sclerosis, neuromyelitis optica spectrum disorder, etc). PRES could also be due to the toxic effects of drugs or other substances. The pathophysiological mechanisms of PRES include impaired autoregulation of cerebral blood flow due to acute arterial hypertension and toxic endotheliotropic effects of endogenous and exogenous factors.
Keywords:
Authors:
Koltsov I.A.
Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies
Shchukin I.A.
Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies
Boiko A.N.
Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies
Received:
28.05.2024
Accepted:
29.05.2024
List of references:
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