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Cherdak M.A.

Pirogov Russian National Research Medical University

Mkhitaryan E.A.

Pirogov Russian National Research Medical University;
Russian Clinical and Research Center of Gerontology Pirogov — Russian National Research Medical University

Tkacheva O.N.

Pirogov Russian National Research Medical University

Differential diagnosis of Alzheimer’s disease and vascular cognitive disorders

Authors:

Cherdak M.A., Mkhitaryan E.A., Tkacheva O.N.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(4‑2): 26‑35

DOI: 10.17116/jnevro202512504226

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Table of contents

DIFFERENTIAL DIAGNOSIS OF ALZHEIMER’S DISEASE AND VASCULAR COGNITIVE DISORDERS
DIFFERENTIAL DIAGNOSIS OF ALZHEIMER’S DISEASE AND VASCULAR COGNITIVE DISORDERS

To cite this article:

Cherdak MA, Mkhitaryan EA, Tkacheva ON. Differential diagnosis of Alzheimer’s disease and vascular cognitive disorders. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(4‑2):26‑35. (In Russ.)
https://doi.org/10.17116/jnevro202512504226

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
 
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Abstract:

Cognitive disorders (CD) are a common problem in the practice of various medical specialities. Among the most common causes of severe CD (dementia) are Alzheimer’s disease (AD) and cerebrovascular diseases. The stage of non-dementia CD precedes dementia. Interventions at the non-dementia stage are believed to be more effective, prolonging the patient’s quality of life at a higher functional level with a decrease in the need for nursing care. Currently, there is a pronounced underdiagnosis of CD, especially AD, which reduces the timely availability of specific drug therapy for patients and adversely affects the prognosis of the disease. The article presents basic information on the pathogenesis and methods of clinical and paraclinical diagnosis of AD and CD of vascular origin. The main markers helping to distinguish these diseases and diagnose them at the predementia stage have been identified.

Keywords:

Alzheimer’s disease
vascular cognitive disorders
differential diagnosis
cerebrovascular diseases
vascular dementia
mild cognitive impairment

Authors:

Cherdak M.A.

Pirogov Russian National Research Medical University

Mkhitaryan E.A.

Pirogov Russian National Research Medical University;
Russian Clinical and Research Center of Gerontology Pirogov — Russian National Research Medical University

Tkacheva O.N.

Pirogov Russian National Research Medical University

Received:

03.02.2025

Accepted:

04.02.2025

Close metadata

References:

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