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Pizov N.A.

Clinical Hospital No. 2

Bakucheva M.V.

Clinical Hospital No. 2

Rechkina O.P.

Clinical and Diagnostic Center «Medinkom Lab»

Features of primary and recurrent ischemic stroke in men aged 18—50 years

Authors:

Pizov N.A., Bakucheva M.V., Rechkina O.P.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(12‑2): 65‑74

DOI: 10.17116/jnevro202412412265

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Table of contents

FEATURES OF PRIMARY AND RECURRENT ISCHEMIC STROKE IN MEN AGED 18—50 YEARS
FEATURES OF PRIMARY AND RECURRENT ISCHEMIC STROKE IN MEN AGED 18—50 YEARS

To cite this article:

Pizov NA, Bakucheva MV, Rechkina OP. Features of primary and recurrent ischemic stroke in men aged 18—50 years. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(12‑2):65‑74. (In Russ.)
https://doi.org/10.17116/jnevro202412412265

Подписка 2025-2 (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
 
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OBJECTIVE

To evaluate the features of primary and recurrent stroke in men aged 18—50 years with atherothrombotic, lacunar, and cardioembolic subtypes.

MATERIAL AND METHODS

A total of 125 men with primary and recurrent stroke were included in the study. The main vascular risk factors and lifestyle-related risk factors were assessed. Neurological, neuroimaging, ultrasound and laboratory examinations were performed. Hemostasis parameters, lipid metabolism and endothelial function parameters were studied.

RESULTS

Among 125 men with ischemic stroke with a median age of 43 years, 104 (83.2%) patients had a primary stroke and 21 (16.8%) patients had a recurrent stroke. Recurrent stroke occurred more frequently in patients with the cardioembolic subtype (26.3%) and with almost equal frequency in patients with the atherothrombotic (13.3%) and lacunar (17.4%) subtypes. In the group as a whole, patients with primary and recurrent strokes did not differ in age (43.1±5.5 and 43.7±4.3 years, respectively). In a comparative analysis of patients with primary and recurrent stroke with different subtypes of stroke, significant differences in the main risk factors, indicators of lipid metabolism, hemostasis and endothelial function were obtained.

CONCLUSION

The study in men, aged 18—50 years, with atherothrombotic, lacunar and cardioembolic subtypes revealed the features of risk factors, indicators of hemostasis system, lipid metabolism and endothelial function in primary and recurrent stroke.

Keywords:

men
primary stroke
recurrent stroke
risk factors

Authors:

Pizov N.A.

Clinical Hospital No. 2

Bakucheva M.V.

Clinical Hospital No. 2

Rechkina O.P.

Clinical and Diagnostic Center «Medinkom Lab»

Received:

27.09.2024

Accepted:

07.10.2024

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