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Ukraintseva Yu.V.

Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Science;
Institute of Biomedical Problems of the Russian Academy of Science

Soloveva A.K.

Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Science

The phenomenon of awakening from sleep and underlying neurophysiological and autonomic mechanisms

Authors:

Ukraintseva Yu.V., Soloveva A.K.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2023;123(5‑2): 21‑27

DOI: 10.17116/jnevro202312305221

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Table of contents

THE PHENOMENON OF AWAKENING FROM SLEEP AND UNDERLYING NEUROPHYSIOLOGICAL AND AUTONOMIC MECHANISMS
THE PHENOMENON OF AWAKENING FROM SLEEP AND UNDERLYING NEUROPHYSIOLOGICAL AND AUTONOMIC MECHANISMS

To cite this article:

Ukraintseva YuV, Soloveva AK. The phenomenon of awakening from sleep and underlying neurophysiological and autonomic mechanisms. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;123(5‑2):21‑27. (In Russ.)
https://doi.org/10.17116/jnevro202312305221

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
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Abstract:

Current research has shown that sleep is not a global process evenly covering the entire brain. The heterogeneity of wakefulness levels in different parts of the brain and differences in their activation thresholds are especially pronounced during the transitions between sleep and wakefulness. During awakening, subcortical brain structures activate first, followed by sensory and motor cortical regions, whereas the associative cortex wakes up much later. Awakening, unlike falling asleep, is not a smooth process. It begins with a short-term sharp activation of the autonomic nervous system and some wake-promoting brain regions. The amplitude of this activity burst is out of proportion to obvious physiological needs and exceeds that observed in later periods of quiet wakefulness. The review discusses the similarities and differences between awakening from sleep and hibernation in hibernating rodents. Data on some clinical consequences of impaired awakening mechanisms are also provided.

Keywords:

sleep
awakening
arousal
autonomic nervous system
arousal threshold
hibernation

Authors:

Ukraintseva Yu.V.

Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Science;
Institute of Biomedical Problems of the Russian Academy of Science

Soloveva A.K.

Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Science

Received:

05.03.2023

Accepted:

10.03.2023

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