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Katunina E.A.

Federal Center of Brain and Neurotechnologies;
Pirogov Russian National Research Medical University

Boyko O.V.

Federal Center for Brain Research and Neurotechnology

Shipilova N.N.

Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation

Kabaeva A.R.

Pirogov Russian National Research Medical University

Boyko A.N.

Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency

A rare clinical case of comorbidity of early-onset Parkinson’s disease and remitting multiple sclerosis

Authors:

Katunina E.A., Boyko O.V., Shipilova N.N., Kabaeva A.R., Boyko A.N.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(7‑2): 99‑103

DOI: 10.17116/jnevro202112107299

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To cite this article:

Katunina EA, Boyko OV, Shipilova NN, Kabaeva AR, Boyko AN. A rare clinical case of comorbidity of early-onset Parkinson’s disease and remitting multiple sclerosis. S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(7‑2):99‑103. (In Russ.)
https://doi.org/10.17116/jnevro202112107299

 
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Comorbidities of extrapyramidal disorders and multiple sclerosis (MS) are rare. The chance of a combination of MS and Parkinson’s disease (PD) is less than 1 in 12.5 million. In total, 42 cases of joint development of these disorders are described in the literature. All described patients had no initial changes in the basal ganglia on MRI, and the development of MS was diagnosed after 1—8 years. Possible common links in the pathogenesis of neurodegenerative disease and MS, as well as the cumulative effect of the two diseases on the severity of axonal degeneration and neuronal loss are discussed. A description of a clinical case of a combination of early onset PD and relapsing-remitting multiple sclerosis is presented.

Keywords:

Parkinson’s disease
multiple sclerosis

Authors:

Katunina E.A.

Federal Center of Brain and Neurotechnologies;
Pirogov Russian National Research Medical University

Boyko O.V.

Federal Center for Brain Research and Neurotechnology

Shipilova N.N.

Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation

Kabaeva A.R.

Pirogov Russian National Research Medical University

Boyko A.N.

Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency

Received:

04.09.2020

Accepted:

30.10.2021

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