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Simaniv T.O.
Neurology Research Center, Moscow
Vasilyev A.V.
Research Center of Neurology, Moscow, Russia
Zakharova M.N.
Research Center of Neurology, Moscow, Russia
Neuromyelitis optica and neuromyelitis optica spectrum disorders
Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2019;119(10‑2): 35‑48
Read: 15497 times
To cite this article:
Simaniv TO, Vasilyev AV, Askarova LSh, Zakharova MN. Neuromyelitis optica and neuromyelitis optica spectrum disorders. S.S. Korsakov Journal of Neurology and Psychiatry.
2019;119(10‑2):35‑48. (In Russ.)
https://doi.org/10.17116/jnevro201911910235
The review is devoted to up-to-date data on epidemiology, aspects of the pathogenesis of neuromyelitis optica (NMO) and neuromyelitis optica spectrum disorders (NMOSD). The authors consider a role of myelin oligodendrocyte glycoprotein immunoglobulin G (MOG-IgG) in the syndromes phenotypically similar to NMO and NMOSD. Special attention is drawn to the methods of MOG-IgG antibodies detection and indications for testing. The approaches and management for treatment and prevention of NMO relapses, risks of complications during pregnancy and immediately after delivery, as well as methods for their prevention and treatment, are described.
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Authors:
Simaniv T.O.
Neurology Research Center, Moscow
Vasilyev A.V.
Research Center of Neurology, Moscow, Russia
Zakharova M.N.
Research Center of Neurology, Moscow, Russia
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