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Goncharov N.G.
Russian Medical Academy of Continuous Professional Education
Nikiforova A.E.
Russian Medical Academy of Continuous Professional Education
Treatment of knee osteoarthritis with autologous stromal-vascular fraction of adipose tissue
Journal: Regenerative Biotechnologies, Preventive, Digital and Predictive Medicine. 2024;1(4): 27‑37
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To cite this article:
Goncharov EN, Koval OA, Bezuglov EN, Goncharov NG, Starostenkov AN, Nikiforova AE. Treatment of knee osteoarthritis with autologous stromal-vascular fraction of adipose tissue. Regenerative Biotechnologies, Preventive, Digital and Predictive Medicine.
2024;1(4):27‑37. (In Russ.)
https://doi.org/10.17116/rbpdpm2024104127
To assess available foreign data on clinical effects of SVF therapy in the treatment of knee osteoarthritis.
We review foreign articles in the PubMed, Medline and Scopus databases using the keywords “SVF therapy”, “knee osteoarthritis”, “regenerative medicine” between 2017 and 2023. There were 172 manuscripts including 103 unique full-text articles suitable for analysis. Of these, 22 manuscripts met the selection criteria.
There are some therapeutic advantages of SVF therapy. Most studies demonstrated the efficacy and safety of this technique, positive clinical results and low incidence of adverse reactions. However, different study design and sample size require caution in interpretation and comparison of results. In addition to positive results, it is necessary to understand methodological limitations of a particular study.
SVF therapy appears to be a promising direction. However, patient safety and conscientious adherence to scientific methodology should always remain a priority.
Keywords:
Authors:
Goncharov N.G.
Russian Medical Academy of Continuous Professional Education
Nikiforova A.E.
Russian Medical Academy of Continuous Professional Education
Received:
10.09.2024
Accepted:
28.09.2024
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