Influence of intestinal microbiota on cardiovascular atherosclerotic diseases and colorectal cancer in elderly patients

Frolova YuV, Dymova OV, Petrenko KN, Polozkova IG, Tsatsurova SA, Charchyan ER, Bedzhanyan AL. Influence of intestinal microbiota on cardiovascular atherosclerotic diseases and colorectal cancer in elderly patients. Regenerative Biotechnologies, Preventive, Digital and Predictive Medicine. 2024;1(1):30‑36. (In Russ.)
https://doi.org/10.17116/rbpdpm2024101130

Подписка 2026 Восстановительные биотехнологии, профилактическая, цифровая и предиктивная медицина (Regenerative Biotechnologies, Preventive, Digital and Predictive Medicine)

Использование инфографики авторами научных работ

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OBJECTIVE

To evaluate the role of intestinal microbiota on development of cardiovascular atherosclerotic diseases and colorectal cancer in an elderly patient.

MATERIAL AND METHODS

We present stage-by-stage treatment of multifocal aortic lesions and colorectal cancer in a patient over 75 years old with preoperative analysis of intestinal microbiota.

RESULTS

Our results regarding 16S rRNA sequencing confirmed the need for vigilance in relation to inflammatory processes and neoplasms in the intestine and cardiovascular diseases (lipometabolism, metabolic syndrome and obesity).

CONCLUSION

This case convincingly demonstrates the feasibility and necessity of intestinal microbiota analysis for differential diagnosis of intestinal metabolites responsible for development and progression of cardiovascular diseases and colorectal cancer in an elderly patient.

Keywords:

intestinal microbiota

cardiac surgery

onco-surgery

colorectal cancer

cardiovascular diseases

Authors:

Frolova Yu.V.

Petrovsky Russian Research Center of Surgery

ORCID: 0000-0002-2075-8543

Dymova O.V.

Petrovsky Russian Research Center of Surgery

ORCID: 0000-0002-3624-4774

Petrenko K.N.

Petrovsky Russian Research Center of Surgery

ORCID: 0000-0003-1705-928X

Polozkova I.G.

Petrovsky Russian Research Center of Surgery

ORCID: 0009-0006-9058-5277

Tsatsurova S.A.

Petrovsky Russian Research Center of Surgery

ORCID: 0000-0002-5165-1204

Charchyan E.R.

Petrovsky Russian Research Center of Surgery

SPIN RSCI: 4641-0523
Scopus AuthorID: 14044681400
ORCID: 0000-0002-0488-2560

Bedzhanyan A.L.

Petrovsky Russian Research Center of Surgery

ORCID: 0000-0002-4377-0035

Received:

17.02.2024

Accepted:

11.03.2024

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