The optimization in the rehabilitation of anosmia after SARS-CoV-2 infection

Kokorina V.E.; Bykov I.A.

doi:https://doi.org/10.17116/otorino20228701133

Kokorina V.E.

Postgraduate Institute for Public Health Workers, Surgical Department

SPIN RSCI: 7040-7416
Scopus AuthorID: 57488869800
ORCID: 0000-0003-0692-0046

Bykov I.A.

Far Eastern State Medical University Public Health and Healthcare Department;
Harbin Medical University School of Public Health Social Medicine Department

SPIN RSCI: 3077-6589
Scopus AuthorID: 57211952835
ORCID: 0000-0003-2375-4625

The optimization in the rehabilitation of anosmia after SARS-CoV-2 infection

Authors:

Kokorina V.E., Bykov I.A.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2022;87(1): 33‑38

DOI: 10.17116/otorino20228701133

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To cite this article:

Kokorina VE, Bykov IA. The optimization in the rehabilitation of anosmia after SARS-CoV-2 infection. Russian Bulletin of Otorhinolaryngology. 2022;87(1):33‑38. (In Russ.)
https://doi.org/10.17116/otorino20228701133

Подписка 2026 Вестник оториноларингологии (Russian Bulletin of Otorhinolaryngology)

Использование инфографики авторами научных работ

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Abstract:

During SARS-CoV-2 pandemic number of patients with olfactory disorders caused by new coronavirus infection substantially increased, making their rehabilitation an issue of the day. We analyzed influence of the drug Sinupret on the restoration dynamic of the olfactory dysfunction associated with SARS-CoV-2 infection. 187 patients with impaired sense of smell associated with SARS-CoV-2 infection were included in this study: test group consisted of 104 cases in which olfactory training methods were combined with the prescription of the drug Sinupret. Control group consisted of 84 patients those undergone olfactory training alone. During study period in 26 patients restoration of the olfactory disorders have not been achieved, due to the virus induced neurodegenerative nature of the lesion. It was observed that in test group odor detection threshold restoration was on average 3.6 days faster than in control group. At the same time, the use of Sinupret was associated with a statistically significant 29.4% decrease of antibiotic prescription frequency for bacterial complications of SARS-CoV-2. Therefore, we assume that the positive effect of Sinupret on SARS-CoV-2 associated anosmia is caused by its antiviral, secretolytic, anti-inflammatory, decongestant and moderately antibacterial effects in the olfactory epithelium.

Keywords:

SARS-CoV-2 virus

anosmia

sense of smell restoration

Sinupret

Authors:

Kokorina V.E.

Postgraduate Institute for Public Health Workers, Surgical Department

SPIN RSCI: 7040-7416
Scopus AuthorID: 57488869800
ORCID: 0000-0003-0692-0046

Bykov I.A.

Far Eastern State Medical University Public Health and Healthcare Department;
Harbin Medical University School of Public Health Social Medicine Department

SPIN RSCI: 3077-6589
Scopus AuthorID: 57211952835
ORCID: 0000-0003-2375-4625

Received:

20.12.2021

Accepted:

24.12.2021

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References:

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