Fungal adenoiditis and tonsillomycosis in children: features of diagnosis and therapy

Krukov A.I.

Sverzhevsky Moscow Scientific and Practical Othorhinolaryngology Center, Moscow

Kunel'skaia V.Ia.

Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii im. L.I. Sverzhevskogo Departamenta zdravookhraneniia Moskvy

Ivoĭlov A.Iu.

Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii Departamenta zdravookhraneniia Moskvy

Izotova G.N.

Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii im. L.I. Sverzhevskogo Departamenta zdravookhraneniia, Moskva, Rossiia, 117152

Shadrin G.B.

Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii im. L.I. Sverzhevskogo Departamenta zdravookhraneniia Moskvy

Machulin A.I.

Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii im. L.I. Sverzhevskogo Departamenta zdravookhraneniia Moskvy, Rossiia, 117152

Fungal adenoiditis and tonsillomycosis in children: features of diagnosis and therapy

Authors:

Krukov A.I., Kunel'skaia V.Ia., Ivoĭlov A.Iu., Izotova G.N., Shadrin G.B., Machulin A.I.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2019;84(2): 78‑83

DOI: 10.17116/otorino20198402178

Downloaded: 196

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Krukov AI, Kunel'skaia VIa, Ivoĭlov AIu, Izotova GN, Shadrin GB, Machulin AI. Fungal adenoiditis and tonsillomycosis in children: features of diagnosis and therapy. Russian Bulletin of Otorhinolaryngology. 2019;84(2):78‑83. (In Russ.)
https://doi.org/10.17116/otorino20198402178

Подписка 2025 (Russian Bulletin of Otorhinolaryngology)

Close metadata

The purpose of the work is to study the current state of the problem of diagnosing and treating fungal adenoiditis and tonsillomycosis in children. This article summarizes the literature data on the predisposing factors and characteristics of the occurrence of fungal infections of adenoid vegetations and tonsils in children. The works present modern approaches to the diagnosis and treatment of children with fungal adenoiditis and tonsillomycosis, depending on the selected genus and the type of fungus. Based on the conducted research, performed on the basis of "The Sverzhevskiy Otorhinolaryngology Healthcare Research Institute", we found that the incidence of fungal adenoiditis in children is 16.4%, and the incidence of tonsillomicosis in children with chronic tonsillitis is 21.5%. The most frequently detected strain in this pathology is C. albicans. In the presented study, a justification of the chosen treatment regimen was made on the basis of the data obtained during microbiological (bacteriological and mycological) studies.

Keywords:

children

fungal adenoiditis

tonsillomycosis

yeast-like fungi of the genus Candida

fluconazole

1% aqueous solution of clotrimazole

001% solution of miramistina

2% solution of silver proteinate

Authors:

Krukov A.I.

Sverzhevsky Moscow Scientific and Practical Othorhinolaryngology Center, Moscow

Kunel'skaia V.Ia.

Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii im. L.I. Sverzhevskogo Departamenta zdravookhraneniia Moskvy

Ivoĭlov A.Iu.

Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii Departamenta zdravookhraneniia Moskvy

Izotova G.N.

Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii im. L.I. Sverzhevskogo Departamenta zdravookhraneniia, Moskva, Rossiia, 117152

Shadrin G.B.

Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii im. L.I. Sverzhevskogo Departamenta zdravookhraneniia Moskvy

Machulin A.I.

Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii im. L.I. Sverzhevskogo Departamenta zdravookhraneniia Moskvy, Rossiia, 117152

List of references:

Karaev ZO, Lebedeva TN. Patogenez kandidoza i allergii k gribam roda Candida. Baku: Izdatel’stvo «Tebib»; 2007. (In Russ.)
Klyasova GA. Mikoticheskie infektsii: klinika, diagnostika, lechenie. Infektsii i antimikrobnaya terapiya. 2000;2:6:184-189. (In Russ.)
Meurman JH, Siikala E, Richardson M, Rautemaa R. Non-Candida albicans Candida yeasts of the oral cavity. In: Mendez—Vilas A., ed. Communicating Current Research and Educational Topics and Trends in Applied Microbiology. Badajoz Formatex. 2007;719-731.
Thompson GR, Patel PK, Kirkpatrick WR, Westbrook SD, Breg D, Erlandsen J, Redding SW, Patterson TF. Oropharyngeal candidiasis in the ear of anti-retroviral therapy. Oral Surg Oral Med Oral Pathol Oral Endod. 2010;109(4):488-495.
Elenov NP, Vasil’eva NV, Stepanova AA, Chilina GA. Candida. Kandidozy. Laboratornaya diagnostika. Pod red. z.d.n. RF prof. Elenova N.P. SPb.: Kosta; 2010. (In Russ.)
Shevlyakov MA, Avalueva EB, Baryshenkova NV. Candida species v kishechnike: klinicheskie aspekty. Problemy meditsinskoi mikologii. 2007;9:(4):4-11. (In Russ.)
Gow NA, Drown AJ, Odds FC. Fungal morphogenesis and host invasion. Curr Opin Microbiol. 2002;5:366-371.
Nikolenko MV. Sutochnaya dinamika fosfolipaznoi aktivnosti C. albicans. Problemy meditsinskoi mikologii. 2010;12:2:49-52. (In Russ.)
Zelenova EG, Zaslavskaya MI, Makhrova GV. Kandidy: ekologiya, morfofunktsional’nye osobennosti i faktory patogennosti. Nizhegorodskii meditsinskii zhurnal. 2002;1:73-84. (In Russ.)
Schaller M, Borelli C, Korting HC, Yube B. Hydrolytic enzy- mes as virulence factors of Candida albicans. Mycoses. 2005;48:365-377.
Smolenski G, Sullivan PA, Gutfield SM. Analysis of secreted aspartic proteinases from Candida albicans: purification and characterization of individual Sap 1, Sap 2 and Sap 3 isoenzymes. Microbiology. 1997;143:349-356.
Dainyak LB, Kunel’skaya VYa. Mikozy verkhnikh dykhatel’nykh putei. M.: Meditsina; 1979. (In Russ.)
Khmel’nitskii OK, Khmel’nitskaya NM. Patomorfologiya mikozov cheloveka. SPb.: Izdatel’skii dom SPbMAPO; 2005. (In Russ.)
Terekhova TN, Kozlovskaya LV, Belik LP, Gorbacheva KA, Karmal’kova EA. Oral’nyi kandidoz u detei. Ucheb.-metod. posobie. Minsk: BGMU; 2008. (In Russ.)
Karpova EP, Tulupov DA, Vagina EE. Terapiya kandidoznogo porazheniya glotki u detei i podrostkov. Pediatriya. 2009;88:5:117-119. (In Russ.)
Rusetskii YuYu, Sedykh TK, Chernyshenko IO, Smirnova VA. Sravnitel’noe bakteriologicheskoe issledovanie mikroflory poverkhnosti i bioptatov mindalin u detei s patologiei limfoadenoidnogo glotochnogo kol’tsa. Pediatriya. 2012;91:2:52-56. (In Russ.)
Shabashova NV, Frolova EV. Immunitet pri orofaringeal’nom kandidoze (obzor). Problemy meditsinskoi mikologii. 2005;7:4: 27-32. (In Russ.)
Buslaeva GN. Lechenie razlichnykh form kandidoza novorozhdennykh i detei rannego vozrasta. Vestnik dermatologii i venerologii. 1997;4:24-28. (In Russ.)
Sakharuk NA, Kozlovskaya AA. Kandidoz: etiologiya, klinika, diagnostika, lechenie. Monografiya. Vitebsk: VGMU; 2010. (In Russ.)
Velichko EV. Usloviya i faktory adgezii gribov roda Candida k epiteliotsitam slizistykh obolochek: Dis... kand. boil. nauk. SPb. 1987. (In Russ.)
Vinokurova SM, Vinogradova MYu, Pronina VB, Ignat’eva SM. Nekotorye kliniko-epidemiologicheskie osobennosti kandidoza u novorozhdennykh nedonoshennykh detei. Problemy meditsinskoi mikologii. 2000;2:2:21-26. (In Russ.)
Kashkin NP, Sheklakov ND. Rukovodstvo po meditsinskoi mikologii. M.: Meditsina; 1978. (In Russ.)
Bondarenko AP, Trotsenko OE, Zaikina ON, Korita TV. Uchastie gribov roda Candida v faringeal’noi patologii u vzroslykh i chasto boleyushchikh detei. Byulleten’ fiziologii i patologii dykhaniya. 2015;58:53-58. (In Russ.)
Kryukov AI, Ivoilov AYu, Kunel’skaya VYa, Shadrin GB, Machulin AI. Eksperimental’noe obosnovanie primeneniya novykh metodik pri terapii gribkovykh adenoiditov u detei. Vestnik otorinolaringologii. 2014;4:43-51. (In Russ.)

Close metadata