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Kutlubaev M.A.
Nevrologicheskoe otdelenie Respublikanskoĭ klinicheskoĭ bol'nitsy im. G.G. Kuvatova
Pal'chun V.T.
Savel'eva E.E.
Kafedra otorinolaringologii s kursom IPO Bashkirskogo gosudarstvennogo meditsinskogo universiteta, Ufa;
Ufimskiĭ filial FGU "Nauchno-klinicheskiĭ tsentr otorinolaringologii FMBA Rossii"
Guseva A.L.
Pirogov Russian National Research Medical University, Moscow
Vascular mechanisms in Meniere’s disease
Journal: Russian Bulletin of Otorhinolaryngology. 2019;84(2): 70‑77
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To cite this article:
Kutlubaev MA, Pal'chun VT, Savel'eva EE, Guseva AL. Vascular mechanisms in Meniere’s disease. Russian Bulletin of Otorhinolaryngology.
2019;84(2):70‑77. (In Russ.)
https://doi.org/10.17116/otorino20198402170
Meniere’s disease (MD) is chronic multifactorial medical condition caused by endolymphatic hydrops, which etiology is unclear. This review highlights possible vascular mechanisms of MD. Impairment of vascular regulation, further ischemic damage of labyrinth and venous drainage pathology could lead to endolymphatic hydrops. Epidemiologic studies reveal high comorbidity of MD and migraine. Both diseases could be the result of trigeminovascular dysfunction. Betahistine, the medication with vascular effect, is widely used in treatment of MD, the effectiveness of calcium channel blockers is evaluated. Keywords: vertigo, Meniere’s disease, endolymphatichydrops, migraine, vascular mechanisms, betahistine.
Authors:
Kutlubaev M.A.
Nevrologicheskoe otdelenie Respublikanskoĭ klinicheskoĭ bol'nitsy im. G.G. Kuvatova
Pal'chun V.T.
Savel'eva E.E.
Kafedra otorinolaringologii s kursom IPO Bashkirskogo gosudarstvennogo meditsinskogo universiteta, Ufa;
Ufimskiĭ filial FGU "Nauchno-klinicheskiĭ tsentr otorinolaringologii FMBA Rossii"
Guseva A.L.
Pirogov Russian National Research Medical University, Moscow
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