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Protasova I.N.

V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Russian Ministry of Health, Krasnoyarsk, Russia, 660022;
Russian-Japanese Centre of Microbiology, Metagenomics and Infectious Diseases of V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Russian Ministry of Health, Krasnoyarsk, Russia, 660022

Per’yanova O.V.

V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Russian Ministry of Health, Krasnoyarsk, Russia, 660022;
Russian-Japanese Centre of Microbiology, Metagenomics and Infectious Diseases of V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Russian Ministry of Health, Krasnoyarsk, Russia, 660022

Podgrushnaya T.S.

V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Russian Ministry of Health, Krasnoyarsk, Russia, 660022

Acute otitis media in the children: etiology and the problems of antibacterial therapy

Authors:

Protasova I.N., Per’yanova O.V., Podgrushnaya T.S.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2017;82(2): 84‑89

DOI: 10.17116/otorino201782284-89

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To cite this article:

Protasova IN, Per’yanova OV, Podgrushnaya TS. Acute otitis media in the children: etiology and the problems of antibacterial therapy. Russian Bulletin of Otorhinolaryngology. 2017;82(2):84‑89. (In Russ.)
https://doi.org/10.17116/otorino201782284-89

Подписка 2025 (Russian Bulletin of Otorhinolaryngology)
 
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The objective of the present review was to summarize the currently available literature data on etiology of acute otitis media in the children, the role of biofilms in the development of this pathology, and sensitivity of its principal causative factors to various antibiotic medications. The secondary objective was to elaborate the practical guidelines for the prevention of acute otitis media in the children.

Keywords:

acute otitis media
children
causative factors
Streptococcus pneumoniae
resistance
antibacterial therapy

Authors:

Protasova I.N.

V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Russian Ministry of Health, Krasnoyarsk, Russia, 660022;
Russian-Japanese Centre of Microbiology, Metagenomics and Infectious Diseases of V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Russian Ministry of Health, Krasnoyarsk, Russia, 660022

Per’yanova O.V.

V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Russian Ministry of Health, Krasnoyarsk, Russia, 660022;
Russian-Japanese Centre of Microbiology, Metagenomics and Infectious Diseases of V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Russian Ministry of Health, Krasnoyarsk, Russia, 660022

Podgrushnaya T.S.

V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Russian Ministry of Health, Krasnoyarsk, Russia, 660022

List of references:

  1. Monasta L, Ronfani L, Marchetti F, Montico M, Vecchi Brumatti L, Bavcar A, Grasso D, Barbiero C, Tamburlini G. Burden of disease caused by otitis media: systematic review and global estimates. PloS One. 2012;7(4):36226. doi:10.1371/journal.pone.0036226
  2. Short KR, Reading PC, Brown LE, Pedersen J, Gilbertson B, Job ER, Edenborough KM, Habets MN, Aldert Zomer A, Hermans PW, Diavatopoulos DA, Wijburg OL. Influenza-induced inflammation drives pneumococcal otitis media. Infection and Immunity. 2013;81(3):645-652. doi:10.1128/IAI.01278-12
  3. Marom T, Nokso-Koivisto J, Chonmaitree T. Viral-bacterial interactions in acute otitis media. Current Allergy and Asthma Reports. 2012;12(6):551-558. doi:10.1007/s11882-012-0303-2
  4. Thomas JP, Berner R, Zahnert T, Dazert S. Acute otitis media — a structured approach. Deutsches Ärzteblatt international. 2014;111(9):151-160. doi:10.3238/arztebl.2014.0151
  5. Murrah KA, Turner RL, Pang B, Perez AC, Reimche JL, King LB, Wren J, Gandhi U, Swords WE, Ornelles DA. Replication of type 5 adenovirus promotes middle ear infection by Streptococcus pneumoniae in the chinchilla model of otitis media. Pathogens and Disease. 2015;73(2):1-8. doi:10.1111/2049-632X.12216
  6. Chonmaitree T, Revai K, Grady JJ, Clos A, Patel JA, Nair S, Fan J, Henrickson KJ. Viral upper respiratory tract infection and otitis media complication in young children. Clinical Infectious Diseases. 2008;46(6):815-823. doi:10.1086/528685
  7. Nokso-Koivisto J, Räty R, Blomqvist S, Kleemola M, Syrjänen R, Pitkäranta A, Kilpi T, Hovi T. Presence of specific viruses in the middle ear fluids and respiratory secretions of young children with acute otitis media. Journal of Medical Virology. 2004;72(2):241-248. doi:10.1002/jmv.10581
  8. Alper CM, Winther B, Mandel EM, Hendley JO, Doyle WJ. Rate of concurrent otitis media in upper respiratory tract infections with specific viruses. Archives of Otolaryngology — Head and Neck Surgery. 2009;135(1):17-21. doi:10.1001/archotol.135.1.17
  9. Longtin J, Bastien M, Gilca R, Leblanc E, de Serres G, Bergeron MG, Boivin G. Human Bocavirus infections in hospitalized children and adults. Emerging Infectious Diseases. 2008;14(2):217-221. doi:10.3201/eid1402.070851
  10. Winther B, Gwaltney JM Jr, Phillips CD, Hendley JO. Radiopaque contrast dye in nasopharynx reaches the middle ear during swallowing and/or yawning. Acta Otolaryngologica. 2005;125(6):625-628. doi:10.1080/00016480510027466
  11. Mills N, Best EJ, Murdoch D, Souter M, Neeff M, Anderson T, Salkeld L, Ahmad Z, Mahadevan M, Barber C, Brown C, Walker C, Walls T. What is behind the ear drum? The microbiology of otitis media and the nasopharyngeal flora in children in the era of pneumococcal vaccination. Journal of Paediatrics and Child Health. 2015;51(3):300-306. doi:10.1111/jpc.12710
  12. Tano K, von Essen R, Eriksson PO, Sjöstedt A. Alloiococcusotitidis — otitis media pathogen or normal bacterial flora? APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica. 2008;116(9):785-790. doi:10.1111/j.1600-0463.2008.01003.x
  13. De Baere T, Vaneechoutte M, Deschaght P, Huyghe J, Dhooge I. The prevalence of middle ear pathogens in the outer ear canal and the nasopharyngeal cavity of healthy young adults. Clinical Microbiology and Infection. 2010;16(7):1031-1035. doi:10.1111/j.1469-0691.2009.02928.x
  14. Marsh RL, Binks MJ, Beissbarth J, Christensen P, Morris PS, Leach AJ, Smith-Vaughan HC. Quantitative PCR of ear discharge from Indigenous Australian children with acute otitis media with perforation supports a role for Alloiococcusotitidis as a secondary pathogen. BMC Ear, Nose, and Throat Disorders. 2012;12:11. doi:10.1186/1472-6815-12-11
  15. Jurcisek JA, Bakaletz LO. Biofilms formed by nontypeable Haemophilus influenzae in vivo contain both double-stranded DNA and type IV pilin protein. Journal of Bacteriology. 2007;189(10):3868-3875. doi:10.1128/JB.01935-06
  16. Parker D, Soong G, Planet P, Brower J, Ratner AJ, Prince A. The NanA neuraminidase of Streptococcus pneumoniae is involved in biofilm formation. Infection and Immunity. 2009;77(9):3722-3730. doi:10.1128/IAI.00228-09
  17. Sanchez CJ, Shivshankar P, Stol K, Trakhtenbroit S, Sullam PM, Sauer K, Hermans PWM, Orihuela CJ. The pneumococcal serine-rich repeat protein is an intra-species bacterial adhesin that promotes bacterial aggregation in vivo and in biofilms. PloS Pathogens. 2010;6(8):1001044. doi:10.1371/journal.ppat.1001044
  18. Pettigrew MM, Gent JF, Revai K, Patel JA, Chonmaitree T. Microbial interactions during upper respiratory tract infections. Emerging Infectious Diseases. 2008;14(10):1584-1591. doi:10.3201/eid1410.080119
  19. Subcommittee of Clinical Practice Guideline for Diagnosis and Management of Acute Otitis Media in Children. Clinical practice guidelines for the diagnosis and management of acute otitis media (AOM) in children in Japan. Auris Nasus Larynx. 2012;39(1):1-8. doi:10.1016/j.anl.2011.09.008
  20. Skaare D, Anthonisen IL, Kahlmeter G, Matuschek E, Natås OB, Steinbakk M, Sundsfjord A, Kristiansen BE. Emergence of clonally related multidrug resistant Haemophilusinfluenzae with penicillin-binding protein 3-mediated resistance to extended-spectrum cephalosporins, Norway, 2006 to 2013. Eurosurveillance. 2014;19(49). pii: 20986. doi:10.2807/1560-7917.ES2014.19.49.20986
  21. Schmitz FJ, Beeck A, Perdikouli M, Boos M, Mayer S, Scheuring S, Köhrer K, Verhoef J, Fluit AC. Production of BRO β-Lactamases and resistance to complement in European Moraxella catarrhalis isolates. Journal of Clinical Microbiology. 2002;40(4):1546-1548. doi:10.1128/JCM.40.4.1546-1548.2002
  22. del Prado G, Ruiz V, Naves P, Rodríguez-Cerrato V, Soriano F, del Carmen Ponte M. Biofilm formation by Streptococcus pneumoniae strains and effects of human serum albumin, ibuprofen, N-acetyl-l-cysteine, amoxicillin, erythromycin, and levofloxacin. Diagnostic Microbiology and Infectious Disease. 2010;67(4):311-318. doi:10.1016/j.diagmicrobio.2010.03.016
  23. Lieberthal AS, Carroll AE, Chonmaitree T, Ganiats TG, Hoberman A, Jackson MA, Joffe MD, Miller DT, RosenfeldRM, Sevilla XD, Schwartz RH, Thomas PA, Tunkel DE. The diagnosis and management of acute otitis media. Pediatrics. 2013;131(3):983.
  24. Courter JD, Baker WL, Nowak KS, Smogowicz LA, Desjardins LL, Coleman CI, Girotto JE. Increased clinical failures when treating acute otitis media with macrolides: ameta-analysis. The Annals of Pharmacotherapy. 2010;44(3):471-478. doi:10.1345/aph.1M344.
  25. Marchisio P, Bellussi L, Di Mauro G, Doria M, Felisati G, Longhi R, Novelli A, Speciale A, Mansi N, Principi N. Acute otitis media: From diagnosis to prevention. Summary of the Italian guideline. International Journal of Pediatric Otorhinolaryngology. 2010;74:1209-1216. doi:10.1016/j.ijporl.2010.08.016
  26. Agence Française de Sécurité Sanitaire des Produits de Santé. Systemic antibiotic treatment in upper and lower respiratory tract infections: official French guidelines. Clinical Microbiology and Infectious Diseases. 2003;9:1162-1178.
  27. Diagnosis and management of childhood otitis media in primary care. https://societyformiddleeardisease.org/Content/SIGN-guideline-OMA-2003.pdf
  28. Otitis media: acute otitis media (AOM) & otitis media with effusion (OME). Guidelines & Protocols Advisory Committee. 2010; http://www2.gov.bc.ca/gov/content/health/practitioner-professional-resources/bc-guidelines/otitis-media#part1_management

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