Experimental study of a new anti-glaucoma intrascleral implant

Slastina K.I.; Sorokoletov G.V.; Trifanenkova I.G.; Plakhotniy M.A.; Erokhina E.V.; Uzunyan D.G.

doi:https://doi.org/10.17116/oftalma202614202116

Slastina K.I.

S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”, Moscow, Russia

ORCID: 0000-0002-8235-2792

Sorokoletov G.V.

S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”, Moscow, Russia

ORCID: 0000-0001-7436-4032

Trifanenkova I.G.

Kaluga branch of the S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”, Kaluga, Russia

ORCID: 0000-0001-9202-5181

Plakhotniy M.A.

Kaluga branch of the S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”, Kaluga, Russia

ORCID: 0000-0002-4099-819X

Erokhina E.V.

Kaluga branch of the S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”, Kaluga, Russia

ORCID: 0000-0001-7320-9209

Uzunyan D.G.

S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”, Moscow, Russia

ORCID: 0009-0003-4164-9607

Experimental study of a new anti-glaucoma intrascleral implant

Authors:

Slastina K.I., Sorokoletov G.V., Trifanenkova I.G., Plakhotniy M.A., Erokhina E.V., Uzunyan D.G.

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Journal: Russian Annals of Ophthalmology. 2026;142(2): 16‑20

DOI: 10.17116/oftalma202614202116

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To cite this article:

Slastina KI, Sorokoletov GV, Trifanenkova IG, Plakhotniy MA, Erokhina EV, Uzunyan DG. Experimental study of a new anti-glaucoma intrascleral implant. Russian Annals of Ophthalmology. 2026;142(2):16‑20. (In Russ.)
https://doi.org/10.17116/oftalma202614202116

Подписка 2026 Вестник офтальмологии (Russian Annals of Ophthalmology)

Использование инфографики авторами научных работ

PURPOSE

This study consisted of an in vivo experiment with the goal of performing instrumental evaluation of the position of a novel anti-glaucoma intrascleral implant.

MATERIAL AND METHODS

This in vivo study was conducted on 5 Chinchilla rabbits (n=5). The main group included 5 right eyes that underwent glaucoma surgery with implantation of the device. The comparison group consisted of 5 left eyes that underwent glaucoma surgery without implant placement. Animals in both groups were followed up for 3 months with biomicroscopy, ultrasound biomicroscopy, and optical coherence tomography (OCT) of the surgery area. At the end of the observation period, the rabbits were removed from the experiment for further research.

RESULTS

The developed intrascleral implant maintained correct position and was clearly visualized within the scleral tissue in animals of the main group throughout the entire observation period (up to 3 months).

CONCLUSION

The new anti-glaucoma intrascleral implant made of polymethylmethacrylate is promising for further research.

Keywords:

intrascleral cavity

polymethyl methacrylate

optical coherence tomography

Authors:

Slastina K.I.

S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”, Moscow, Russia

ORCID: 0000-0002-8235-2792

Sorokoletov G.V.

S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”, Moscow, Russia

ORCID: 0000-0001-7436-4032

Trifanenkova I.G.

Kaluga branch of the S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”, Kaluga, Russia

ORCID: 0000-0001-9202-5181

Plakhotniy M.A.

Kaluga branch of the S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”, Kaluga, Russia

ORCID: 0000-0002-4099-819X

Erokhina E.V.

Kaluga branch of the S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”, Kaluga, Russia

ORCID: 0000-0001-7320-9209

Uzunyan D.G.

S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”, Moscow, Russia

ORCID: 0009-0003-4164-9607

Received:

25.05.2025

Accepted:

08.09.2025

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References:

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