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Bystrov A.M.

Chelyabinsk Regional Clinical Hospital

Davydova E.V.

Chelyabinsk Regional Clinical Hospital;
South-Ural State Medical University

Kuznetzov A.A.

Chelyabinsk Regional Clinical Hospital

Sumina M.S.

Chelyabinsk Regional Clinical Hospital

Use of ozone therapy in the treatment of complications following penetrating keratoplasty for rosacea-associated keratitis

Authors:

Bystrov A.M., Davydova E.V., Kuznetzov A.A., Sumina M.S.

More about the authors

Journal: Russian Annals of Ophthalmology. 2025;141(4): 66‑72

DOI: 10.17116/oftalma202514104166

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Table of contents

USE OF OZONE THERAPY IN THE TREATMENT OF COMPLICATIONS FOLLOWING PENETRATING KERATOPLASTY FOR ROSACEA-ASSOCIATED KERATITIS
USE OF OZONE THERAPY IN THE TREATMENT OF COMPLICATIONS FOLLOWING PENETRATING KERATOPLASTY FOR ROSACEA-ASSOCIATED KERATITIS

To cite this article:

Bystrov AM, Davydova EV, Kuznetzov AA, Sumina MS. Use of ozone therapy in the treatment of complications following penetrating keratoplasty for rosacea-associated keratitis. Russian Annals of Ophthalmology. 2025;141(4):66‑72. (In Russ.)
https://doi.org/10.17116/oftalma202514104166

Подписка 2026 Вестник офтальмологии (Russian Annals of Ophthalmology)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Rosacea is a chronic inflammatory dermatosis, one manifestation of which involves pathological processes in various ocular structures. The most severe form is rosacea-associated keratitis. Given the multifactorial etiology and pathogenesis, this condition remains unpredictable and resistant to treatment. This study presents a clinical case of using ozone therapy in the management of complications following penetrating keratoplasty in the setting of rosacea-associated keratitis and demonstrates the therapeutic effectiveness of ozone therapy as part of a comprehensive approach to managing post-keratoplasty complications in patients with rosacea-associated keratitis. The inclusion of ozone therapy led to clinical and functional improvement by day 10. By day 60, corneal syndrome manifestations were minimal, the graft remained transparent, and significant regression of neovascularization was observed. Due to the pronounced anti-inflammatory and reparative effects of therapeutic ozone concentrations, its use in this context is pathogenetically justified.

Keywords:

rosacea-associated keratitis
penetrating keratoplasty
inflammation
ozone therapy

Authors:

Bystrov A.M.

Chelyabinsk Regional Clinical Hospital

Davydova E.V.

Chelyabinsk Regional Clinical Hospital;
South-Ural State Medical University

Kuznetzov A.A.

Chelyabinsk Regional Clinical Hospital

Sumina M.S.

Chelyabinsk Regional Clinical Hospital

Received:

19.08.2024

Accepted:

25.11.2024

Close metadata

References:

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