Aim — to evaluate treatment results in far-advanced glaucoma patients. Material and methods. A total of 81 patients (81 eyes) with far-advanced open-angle glaucoma were followed up. The patients were divided into two groups by the treatment they received. In group 1 (41 patients, 41 eyes) a complex treatment scheme was applied, which included surgical, medicinal, and physiotherapeutic measures, in particular, sinus trabeculectomy (STE) plus posterior scleral trepanation (PST), a 10-day course of subconjunctival Cytoflavin 10 mg 0.5 ml, and magnetolaser stimulation of the optic nerve. Group 2 (controls) consisted of the rest 40 patients (40 eyes), who received just STE and PST. Results. The combination approach has yielded visual improvements and glaucoma stabilization in 87% of patients from group 1 by the end of the first year of follow-up, while in group 2 positive changes were found in only 68% of patients.