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Kharchenko E.P.

Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia

Arterial hypertension: An expanding pathogenic continuum and therapeutic limitations

Authors:

Kharchenko E.P.

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Journal: Therapeutic Archive. 2015;87(1): 100‑104

DOI: 10.17116/terarkh2015871100-104

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ARTERIAL HYPERTENSION: AN EXPANDING PATHOGENIC CONTINUUM AND THERAPEUTIC LIMITATIONS
ARTERIAL HYPERTENSION: AN EXPANDING PATHOGENIC CONTINUUM AND THERAPEUTIC LIMITATIONS

To cite this article:

Kharchenko EP. Arterial hypertension: An expanding pathogenic continuum and therapeutic limitations. Therapeutic Archive. 2015;87(1):100‑104. (In Russ.)
https://doi.org/10.17116/terarkh2015871100-104

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Abstract:

The paper considers the role of the immune system, endoplasmic network stress, metabolic dysregulation, and epigenetic mechanisms in the pathogenesis of essential hypertension, as well as the limited possibilities of therapy with existing antihypertensive agents.

Keywords:

essential hypertension
pathogenesis
immune system
endoplasmic network
epigenetics
therapy

Authors:

Kharchenko E.P.

Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia

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